Literature DB >> 22444586

For MutY, it's all about the OG.

Robert W Sobol1.   

Abstract

MutY and its human ortholog, MUTYH, repair a specific form of DNA damage: adenine mis-paired with the oxidatively modified form of deoxyguanosine, 8-oxo-7,8-dihydro-2'-deoxyguanosine. In a recent issue of Chemistry & Biology, Brinkmeyer et al. utilized mutant forms of MutY to reveal the critical residues in MutY that are required for this selectivity and specificity. Copyright Â
© 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22444586      PMCID： PMC3891578          DOI： 10.1016/j.chembiol.2012.03.002

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  10 in total

Review 1.  The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine).

Authors:  M L Michaels; J H Miller
Journal:  J Bacteriol       Date:  1992-10       Impact factor: 3.490

Review 2.  Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage.

Authors:  David Svilar; Eva M Goellner; Karen H Almeida; Robert W Sobol
Journal:  Antioxid Redox Signal       Date:  2010-10-28       Impact factor: 8.401

Review 3.  A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification.

Authors:  Karen H Almeida; Robert W Sobol
Journal:  DNA Repair (Amst)       Date:  2007-03-06

Review 4.  Base-excision repair of oxidative DNA damage.

Authors:  Sheila S David; Valerie L O'Shea; Sucharita Kundu
Journal:  Nature       Date:  2007-06-21       Impact factor: 49.962

Review 5.  DNA damage, aging, and cancer.

Authors:  Jan H J Hoeijmakers
Journal:  N Engl J Med       Date:  2009-10-08       Impact factor: 91.245

6.  Catalytic contributions of key residues in the adenine glycosylase MutY revealed by pH-dependent kinetics and cellular repair assays.

Authors:  Megan K Brinkmeyer; Mary Ann Pope; Sheila S David
Journal:  Chem Biol       Date:  2012-02-24

7.  Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents.

Authors:  H Kasai; S Nishimura
Journal:  Nucleic Acids Res       Date:  1984-02-24       Impact factor: 16.971

Review 8.  Colorectal cancer and inherited mutations in base-excision repair.

Authors:  Elizabeth Chow; Christina Thirlwell; Finlay Macrae; Lara Lipton
Journal:  Lancet Oncol       Date:  2004-10       Impact factor: 41.316

9.  Structure of DNA polymerase beta with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential.

Authors:  Joseph M Krahn; William A Beard; Holly Miller; Arthur P Grollman; Samuel H Wilson
Journal:  Structure       Date:  2003-01       Impact factor: 5.006

10.  TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

Authors:  A Phillip West; Igor E Brodsky; Christoph Rahner; Dong Kyun Woo; Hediye Erdjument-Bromage; Paul Tempst; Matthew C Walsh; Yongwon Choi; Gerald S Shadel; Sankar Ghosh
Journal:  Nature       Date:  2011-04-28       Impact factor: 49.962
  10 in total
  7 in total

Review 1.  Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleotide pool to genotoxic damage.

Authors:  Priyamvada Rai; Robert W Sobol
Journal:  DNA Repair (Amst)       Date:  2019-03-02

2.  Alkylation sensitivity screens reveal a conserved cross-species functionome.

Authors:  David Svilar; Madhu Dyavaiah; Ashley R Brown; Jiang-bo Tang; Jianfeng Li; Peter R McDonald; Tong Ying Shun; Andrea Braganza; Xiao-hong Wang; Salony Maniar; Claudette M St Croix; John S Lazo; Ian F Pollack; Thomas J Begley; Robert W Sobol
Journal:  Mol Cancer Res       Date:  2012-10-04       Impact factor: 5.852

Review 3.  Base excision repair facilitates a functional relationship between Guanine oxidation and histone demethylation.

Authors:  Jianfeng Li; Andrea Braganza; Robert W Sobol
Journal:  Antioxid Redox Signal       Date:  2013-02-28       Impact factor: 8.401

4.  Identification of genes involved in low aminoglycoside-induced SOS response in Vibrio cholerae: a role for transcription stalling and Mfd helicase.

Authors:  Zeynep Baharoglu; Anamaria Babosan; Didier Mazel
Journal:  Nucleic Acids Res       Date:  2013-12-06       Impact factor: 16.971

5.  RpoS plays a central role in the SOS induction by sub-lethal aminoglycoside concentrations in Vibrio cholerae.

Authors:  Zeynep Baharoglu; Evelyne Krin; Didier Mazel
Journal:  PLoS Genet       Date:  2013-04-11       Impact factor: 5.917

6.  Repair of oxidative DNA base damage in the host genome influences the HIV integration site sequence preference.

Authors:  Geoffrey R Bennett; Ryan Peters; Xiao-hong Wang; Jeungphill Hanne; Robert W Sobol; Ralf Bundschuh; Richard Fishel; Kristine E Yoder
Journal:  PLoS One       Date:  2014-07-22       Impact factor: 3.240

7.  DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity.

Authors:  Jianfeng Li; David Svilar; Steven McClellan; Jung-Hyun Kim; Eun-Young Erin Ahn; Conchita Vens; David M Wilson; Robert W Sobol
Journal:  Oncotarget       Date:  2018-08-03
  7 in total

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