Literature DB >> 22444155

Tetrahymena in the classroom.

Joshua J Smith1, Emily A Wiley, Donna M Cassidy-Hanley.   

Abstract

Tetrahymena has been a useful model in basic research in part due to the fact it is easy to grow in culture and exhibits a range of complex processes, all within a single cell. For these same reasons Tetrahymena has shown enormous potential as a teaching tool for fundamental principles of biology at multiple science education levels that can be integrated into K-12 classrooms and undergraduate and graduate college laboratory courses. These Tetrahymena-based teaching modules are inquiry-based experiences that are also effective at teaching scientific concepts, retaining students in science, and exciting students about the scientific process. Two learning communities have been developed that utilize Tetrahymena-based teaching modules. Advancing Secondary Science Education with Tetrahymena (ASSET) and the Ciliate Genomics Consortium (CGC) have developed modules for K-12 students and college-level curriculums, respectively. These modules range from addressing topics in ecology, taxonomy, and environmental toxicity to more advanced concepts in biochemistry, proteomics, bioinformatics, cell biology, and molecular biology. An overview of the current modules and their learning outcomes are discussed, as are assessment, dissemination, and sustainability strategies for K-12 and college-level curriculum. Copyright Â
© 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22444155      PMCID: PMC3587665          DOI: 10.1016/B978-0-12-385967-9.00016-5

Source DB:  PubMed          Journal:  Methods Cell Biol        ISSN: 0091-679X            Impact factor:   1.441


  5 in total

Review 1.  Functional genomics: the coming of age for Tetrahymena thermophila.

Authors:  Aaron P Turkewitz; Eduardo Orias; Geoffrey Kapler
Journal:  Trends Genet       Date:  2002-01       Impact factor: 11.639

Review 2.  DNA elimination in ciliates: transposon domestication and genome surveillance.

Authors:  Douglas L Chalker; Meng-Chao Yao
Journal:  Annu Rev Genet       Date:  2011-09-09       Impact factor: 16.830

Review 3.  RNA-directed epigenetic regulation of DNA rearrangements.

Authors:  Kazufumi Mochizuki
Journal:  Essays Biochem       Date:  2010-09-20       Impact factor: 8.000

Review 4.  Out with a bang! Tetrahymena as a model system to study secretory granule biogenesis.

Authors:  Aaron P Turkewitz
Journal:  Traffic       Date:  2004-02       Impact factor: 6.215

5.  Microarray analyses of gene expression during the Tetrahymena thermophila life cycle.

Authors:  Wei Miao; Jie Xiong; Josephine Bowen; Wei Wang; Yifan Liu; Olga Braguinets; Jorg Grigull; Ronald E Pearlman; Eduardo Orias; Martin A Gorovsky
Journal:  PLoS One       Date:  2009-02-10       Impact factor: 3.240

  5 in total
  3 in total

Review 1.  Tetrahymena as a Unicellular Model Eukaryote: Genetic and Genomic Tools.

Authors:  Marisa D Ruehle; Eduardo Orias; Chad G Pearson
Journal:  Genetics       Date:  2016-06       Impact factor: 4.562

2.  A Multiweek Project Examining the Chemotactic Behavior of Tetrahymena in an Undergraduate Biology Laboratory.

Authors:  Rachel Hongo; Robert T Grammer; Christopher E Barton
Journal:  J Microbiol Biol Educ       Date:  2020-02-28

3.  Immediate dissemination of student discoveries to a model organism database enhances classroom-based research experiences.

Authors:  Emily A Wiley; Nicholas A Stover
Journal:  CBE Life Sci Educ       Date:  2014       Impact factor: 3.325

  3 in total

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