| Literature DB >> 22443275 |
Luiz C Dias1, Marco A B Ferreira.
Abstract
A stereoselective total synthesis of the reported structure of goniotrionin (4) has been accomplished. The key steps involved the opening of a chiral epoxide, a highly diastereoselective Mukaiyama aerobic oxidative cyclization, a selective 1,2-syn Mukaiyama aldol reaction, and a Noyori reduction.Entities:
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Year: 2012 PMID： 22443275 DOI： 10.1021/jo3004106
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354