Literature DB >> 22442140

Metformin, metabolic stress, and mitochondria. Focus on "A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells".

Mary C Sugden, Mark J Holness.   

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Year:  2012        PMID: 22442140     DOI: 10.1152/ajpcell.00090.2012

Source DB:  PubMed          Journal:  Am J Physiol Cell Physiol        ISSN: 0363-6143            Impact factor:   4.249


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  2 in total

1.  A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells.

Authors:  Lauren E Nelson; Rudy J Valentine; José M Cacicedo; Marie-Soleil Gauthier; Yasuo Ido; Neil B Ruderman
Journal:  Am J Physiol Cell Physiol       Date:  2012-02-29       Impact factor: 4.249

2.  Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway.

Authors:  Young Mi Song; Yong-ho Lee; Ji-Won Kim; Dong-Sik Ham; Eun-Seok Kang; Bong Soo Cha; Hyun Chul Lee; Byung-Wan Lee
Journal:  Autophagy       Date:  2015       Impact factor: 16.016

  2 in total

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