BACKGROUND: Posthepatectomy liver failure (PHLF) is one of the most serious complications after liver resection and is still reported in up to 8% after liver resection. AIMS: To provide an overview about the current status of risk analysis and definition of PHLF. Prevention and treatment is also discussed. METHODS: A literature review was carried out on PubMed using the terms 'liver failure', 'posthepatectomy' and 'liver surgery' to search relevant papers. DISCUSSION: PHLF remains a serious problem in patients undergoing major liver resection. Adequate preoperative risk assessment and an optimal postoperative treatment are essential for PHLF prevention.
BACKGROUND: Posthepatectomy liver failure (PHLF) is one of the most serious complications after liver resection and is still reported in up to 8% after liver resection. AIMS: To provide an overview about the current status of risk analysis and definition of PHLF. Prevention and treatment is also discussed. METHODS: A literature review was carried out on PubMed using the terms 'liver failure', 'posthepatectomy' and 'liver surgery' to search relevant papers. DISCUSSION: PHLF remains a serious problem in patients undergoing major liver resection. Adequate preoperative risk assessment and an optimal postoperative treatment are essential for PHLF prevention.
Authors: Michael N Thomas; Ernst Weninger; Martin Angele; Florian Bösch; Sebastian Pratschke; Joachim Andrassy; Markus Rentsch; Manfred Stangl; Werner Hartwig; Jens Werner; Markus Guba Journal: HPB (Oxford) Date: 2015-01-08 Impact factor: 3.647
Authors: Sarah B Fisher; Peter J Kneuertz; Rebecca M Dodson; Sameer H Patel; Shishir K Maithel; Juan M Sarmiento; Maria C Russell; Kenneth Cardona; Michael A Choti; Charles A Staley; Timothy M Pawlik; David A Kooby Journal: HPB (Oxford) Date: 2013-07-22 Impact factor: 3.647