Literature DB >> 22440910

Type I interferons: diversity of sources, production pathways and effects on immune responses.

Melissa Swiecki1, Marco Colonna.   

Abstract

Type I interferons (IFN-I) were first described over 50 years ago as factors produced by cells that interfere with virus replication and promote an antiviral state. Innate and adaptive immune responses to viruses are also greatly influenced by IFN-I. In this article we discuss the diversity of cellular sources of IFN-I and the pathways leading to IFN-I production during viral infections. Finally, we discuss the effects of IFN-I on cells of the immune system with emphasis on dendritic cells.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 22440910      PMCID: PMC3572907          DOI: 10.1016/j.coviro.2011.10.026

Source DB:  PubMed          Journal:  Curr Opin Virol        ISSN: 1879-6257            Impact factor:   7.090


  196 in total

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10.  Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes.

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  43 in total

1.  Long Noncoding RNA Signatures Induced by Toll-Like Receptor 7 and Type I Interferon Signaling in Activated Human Plasmacytoid Dendritic Cells.

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Journal:  J Interferon Cytokine Res       Date:  2018-09       Impact factor: 2.607

2.  Measurement of Antiviral Effect and Innate Immune Response During Treatment of Primary Woodchuck Hepatocytes.

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Journal:  Methods Mol Biol       Date:  2017

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4.  Plasmacytoid dendritic cells are productively infected and activated through TLR-7 early after arenavirus infection.

Authors:  Mónica Macal; Gavin M Lewis; Stefan Kunz; Richard Flavell; James A Harker; Elina I Zúñiga
Journal:  Cell Host Microbe       Date:  2012-06-14       Impact factor: 21.023

5.  Membrane Perturbation-Associated Ca2+ Signaling and Incoming Genome Sensing Are Required for the Host Response to Low-Level Enveloped Virus Particle Entry.

Authors:  David N Hare; Susan E Collins; Subhendu Mukherjee; Yueh-Ming Loo; Michael Gale; Luke J Janssen; Karen L Mossman
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Review 6.  Animal Models for the Study of Nucleic Acid Immunity: Novel Tools and New Perspectives.

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Review 8.  Neoplasms derived from plasmacytoid dendritic cells.

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9.  Efficient antigen cross-presentation through coating conventional aluminum adjuvant particles with PEI.

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10.  Differential responses of plasmacytoid dendritic cells to influenza virus and distinct viral pathogens.

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