Literature DB >> 22440484

An exploration of modifiable risk factors for depression after spinal cord injury: which factors should we target?

Charles H Bombardier1, Jesse R Fann, Denise G Tate, J Scott Richards, Catherine S Wilson, Ann Marie Warren, Nancy R Temkin, Allen W Heinemann.   

Abstract

OBJECTIVE: To identify modifiable risk factors for depression in people with spinal cord injury (SCI).
DESIGN: Cross-sectional survey.
SETTING: Outpatient and community settings. PARTICIPANTS: Community-residing people with SCI (N=244; 77% men, 61% white; mean age, 43.1y; 43% with tetraplegia) who were at least 1 month postinjury.
INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Depression severity (Patient Health Questionnaire-9 [PHQ-9]), physical activity (International Physical Activity Questionnaire [IPAQ]), pleasant and rewarding activities (Environment Rewards Observation Scale [EROS]), and self-efficacy to manage the effects of SCI (Modified Lorig Chronic Disease Self-Management Scale).
RESULTS: Greater depression severity was associated with being 20 to 29 years of age, not completing high school, not working or attending school, and being ≤4 years post-SCI. After controlling for demographic and injury characteristics (adjusted R(2)=.13), lower EROS scores (change in adjusted R(2)=.34) and lower self-efficacy (change in R(2)=.13) were independent predictors of higher PHQ-9 scores. Contrary to predictions, physical activity as measured by the IPAQ did not predict depression severity.
CONCLUSIONS: Our findings suggest that having fewer rewarding activities, and to a lesser extent, having less confidence in one's ability to manage the effects of SCI are independent predictors of greater depression severity after SCI. Interventions such as behavior activation, designed to increase rewarding activities, may represent an especially promising approach to treating depression in this population.
Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22440484     DOI: 10.1016/j.apmr.2011.12.020

Source DB:  PubMed          Journal:  Arch Phys Med Rehabil        ISSN: 0003-9993            Impact factor:   3.966


  21 in total

1.  Endoplasmic Reticulum Stress and Disrupted Neurogenesis in the Brain Are Associated with Cognitive Impairment and Depressive-Like Behavior after Spinal Cord Injury.

Authors:  Junfang Wu; Zaorui Zhao; Alok Kumar; Marta M Lipinski; David J Loane; Bogdan A Stoica; Alan I Faden
Journal:  J Neurotrauma       Date:  2016-05-16       Impact factor: 5.269

2.  Assessment of depression in a rodent model of spinal cord injury.

Authors:  Kelsey Luedtke; Sioui Maldonado Bouchard; Sarah A Woller; Mary Katherine Funk; Miriam Aceves; Michelle A Hook
Journal:  J Neurotrauma       Date:  2014-05-08       Impact factor: 5.269

3.  Management of Mental Health Disorders, Substance Use Disorders, and Suicide in Adults with Spinal Cord Injury: Clinical Practice Guideline for Healthcare Providers.

Authors:  Charles H Bombardier; Casey B Azuero; Jesse R Fann; Donald D Kautz; J Scott Richards; Sunil Sabharwal
Journal:  Top Spinal Cord Inj Rehabil       Date:  2021

4.  The association between injustice perception and psychological outcomes in an inpatient spinal cord injury sample: the mediating effects of anger.

Authors:  Z Trost; W Scott; M T Buelow; L Nowlin; B Turan; A Boals; K R Monden
Journal:  Spinal Cord       Date:  2017-05-30       Impact factor: 2.772

5.  Prevalence of depression, fatigue, and sleep disturbances in patients with myelopathy: Their relation with functional and neurological recovery.

Authors:  Nitin Menon; Anupam Gupta; Meeka Khanna; Arun B Taly; K Thennarasu
Journal:  J Spinal Cord Med       Date:  2016-02-15       Impact factor: 1.985

6.  Relationship Between Comorbidities and Employment Among Veterans with Spinal Cord Injury.

Authors:  Lance L Goetz; Lisa Ottomanelli; Scott D Barnett; Bryce Sutton; Eni Njoh
Journal:  Top Spinal Cord Inj Rehabil       Date:  2017-09-27

7.  A randomized controlled trial of venlafaxine XR for major depressive disorder after spinal cord injury: Methods and lessons learned.

Authors:  Charles H Bombardier; Jesse R Fann; Catherine S Wilson; Allen W Heinemann; J Scott Richards; Ann Marie Warren; Larry Brooks; Catherine A Warms; Nancy R Temkin; Denise G Tate
Journal:  J Spinal Cord Med       Date:  2013-11-26       Impact factor: 1.985

8.  Associations Between Doing Planned Exercise and Probable Major Depressive Disorder in Individuals Following Spinal Cord Injury.

Authors:  Catherine Jefferson VanDerwerker; Yue Cao; Chris M Gregory; James S Krause
Journal:  Top Spinal Cord Inj Rehabil       Date:  2020

9.  Depression and depression treatment in women with spinal cord injury.

Authors:  Susan Robinson-Whelen; Heather B Taylor; Rosemary B Hughes; Lisa Wenzel; Margaret A Nosek
Journal:  Top Spinal Cord Inj Rehabil       Date:  2014

10.  Depression Following Spinal Cord Injury: Its Relationship to Demographic and Socioeconomic Indicators.

Authors:  Zahra Khazaeipour; Seyedeh-Mohadeseh Taheri-Otaghsara; Maryam Naghdi
Journal:  Top Spinal Cord Inj Rehabil       Date:  2015-04-12
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