OBJECTIVES: To compare REM sleep chin EMG quantitative features between Parkinson's disease (PD) patients with or without REM sleep behavior disorder (RBD). SUBJECTS AND METHODS: Twenty-seven consecutive PD patients (mean age 67.9 years) and 19 normal controls (mean age 67.5 years) were enrolled. Detailed clinical, laboratory, and polysomnographic studies were obtained in all participants and characteristics of chin electromyographic amplitude during rapid eye movements sleep were analyzed by means of an automatic quantitative approach (Atonia Index). RESULTS: Sixteen of the 27 patients were affected by RBD. An Atonia Index below 0.90 showed high sensitivity (0.938) and specificity (0.909) for the diagnosis of RBD within the group of PD patients. CONCLUSION: This study recommends the Atonia Index as an objective measure to support and aid the diagnosis of RBD in PD.
OBJECTIVES: To compare REM sleep chin EMG quantitative features between Parkinson's disease (PD) patients with or without REM sleep behavior disorder (RBD). SUBJECTS AND METHODS: Twenty-seven consecutive PDpatients (mean age 67.9 years) and 19 normal controls (mean age 67.5 years) were enrolled. Detailed clinical, laboratory, and polysomnographic studies were obtained in all participants and characteristics of chin electromyographic amplitude during rapid eye movements sleep were analyzed by means of an automatic quantitative approach (Atonia Index). RESULTS: Sixteen of the 27 patients were affected by RBD. An Atonia Index below 0.90 showed high sensitivity (0.938) and specificity (0.909) for the diagnosis of RBD within the group of PDpatients. CONCLUSION: This study recommends the Atonia Index as an objective measure to support and aid the diagnosis of RBD in PD.
Authors: Stuart J McCarter; Erik K St Louis; David J Sandness; Ethan J Duwell; Paul C Timm; Bradley F Boeve; Michael H Silber Journal: Sleep Med Date: 2016-05-11 Impact factor: 3.492
Authors: Raffaele Ferri; Sara Marelli; Filomena I I Cosentino; Francesco Rundo; Luigi Ferini-Strambi; Marco Zucconi Journal: J Clin Sleep Med Date: 2013-03-15 Impact factor: 4.062
Authors: Lama M Chahine; Shilpa R Kauta; Joseph T Daley; Charles R Cantor; Nabila Dahodwala Journal: Parkinsonism Relat Disord Date: 2014-04-18 Impact factor: 4.891
Authors: Stuart J McCarter; Erik K St Louis; Ethan J Duwell; Paul C Timm; David J Sandness; Bradley F Boeve; Michael H Silber Journal: Sleep Date: 2014-10-01 Impact factor: 5.849
Authors: Stuart J McCarter; Grace M Tabatabai; Ho-Yann Jong; David J Sandness; Paul C Timm; Katie L Johnson; Allison R McCarter; Rodolfo Savica; Prashanthi Vemuri; Mary M Machulda; Kejal Kantarci; Michelle M Mielke; Bradley F Boeve; Michael H Silber; Erik K St Louis Journal: Neurology Date: 2019-12-12 Impact factor: 9.910