OBJECTIVES: To verify whether Doppler velocimetry on the uterine arteries can be used to single out abnormal hemodynamic adjustments in the uteroplacental district and to prognose adverse gestational outcomes in pregnant women with autoimmune and trombophilic disease. METHODS: The study included 67 patients divided into 3 groups selected by a developed pathology. Attention was given to the performance of the Resistance Index (RI) in Doppler velocimetry checks at 10th, 16th-18th, 21st and 28th weeks of gestation. RESULTS: A significant correlation between Doppler values at week 21st and development of preeclampsia was observed (p <0.05) in the three patient groups. High Doppler values at the 21st week were found to be strongly associated (p <0.01) with preterm delivery. We also observed a significant correlation (p <0.05) between high Doppler values at week 21st and low weight at birth. Doppler was found to have a predictive power for gestational adverse outcomes already at week 16th. CONCLUSION: RI values of more than 0.58 (taken as a cut-off) at 16/18th weeks allowed us to identify the category most at risk, if confirmed at 21 weeks.
OBJECTIVES: To verify whether Doppler velocimetry on the uterine arteries can be used to single out abnormal hemodynamic adjustments in the uteroplacental district and to prognose adverse gestational outcomes in pregnant women with autoimmune and trombophilic disease. METHODS: The study included 67 patients divided into 3 groups selected by a developed pathology. Attention was given to the performance of the Resistance Index (RI) in Doppler velocimetry checks at 10th, 16th-18th, 21st and 28th weeks of gestation. RESULTS: A significant correlation between Doppler values at week 21st and development of preeclampsia was observed (p <0.05) in the three patient groups. High Doppler values at the 21st week were found to be strongly associated (p <0.01) with preterm delivery. We also observed a significant correlation (p <0.05) between high Doppler values at week 21st and low weight at birth. Doppler was found to have a predictive power for gestational adverse outcomes already at week 16th. CONCLUSION: RI values of more than 0.58 (taken as a cut-off) at 16/18th weeks allowed us to identify the category most at risk, if confirmed at 21 weeks.
Authors: F Carmona; J Font; M Azulay; M Creus; F Fábregues; R Cervera; B Puerto; J Balasch Journal: Am J Reprod Immunol Date: 2001-10 Impact factor: 3.886
Authors: O Gómez; J M Martínez; F Figueras; M Del Río; V Borobio; B Puerto; O Coll; V Cararach; J A Vanrell Journal: Ultrasound Obstet Gynecol Date: 2005-10 Impact factor: 7.299
Authors: L Caforio; A C Testa; C Mastromarino; B Carducci; M Ciampelli; D Mansueto; A Caruso Journal: Fetal Diagn Ther Date: 1999 Jul-Aug Impact factor: 2.587
Authors: D Le Thi Huong; B Wechsler; D Vauthier-Brouzes; P Duhaut; N Costedoat; M R Andreu; G Lefebvre; J-C Piette Journal: Rheumatology (Oxford) Date: 2005-10-25 Impact factor: 7.580