Literature DB >> 22439062

Comparison of maternal and neonatal outcomes in women with HELLP syndrome and women with severe preeclampsia without HELLP syndrome.

Abdulkadir Turgut1, Oya Demirci, Elif Demirci, Mehmet Uludoğan.   

Abstract

OBJECTIVE: To examine and to compare postpartum maternal and neonatal complications and morbidities in women with HELLP syndrome (HELLP group) and women with severe preeclampsia without HELLP syndrome (severe preeclamptic group).
METHODS: In this retrospective study, 111 patients in the HELLP group were matched with 467 patients in the severe preeclamptic group according to maternal and neonatal complications and morbidities.
RESULTS: The rate of transfusion of blood products and acute renal failure was significantly greater in women with HELLP syndrome. One maternal mortality (0.9 % ) was found in women withHELLP syndrome, and no maternal mortality in women in severe preeclamptic group a. There were significant differences between the HELLP group and the severe preeclamptic group in neonatal mortality and morbidity. It was found that HELLP syndrome cases had significantly lower gestational age and fetal bodyweight. The simultaneous presence of HELLP syndrome and preeclampsia, along with oliguria, ascites, thrombocytopenia, elevated liver enzymes and caesarean delivery, was associated with post-partum complications.
CONCLUSION: This study shows that maternal and neonatal morbidity and mortality are increased in pregnancies complicated by severe preeclampsia with HELLP syndrome. Neonatal mortality and morbidity appear to be influenced primarily by gestational age at delivery.

Entities:  

Keywords:  HELLP syndrome; maternal mortality.; neonatal outcome; pre-eclampsia

Year:  2010        PMID: 22439062      PMCID: PMC3279181     

Source DB:  PubMed          Journal:  J Prenat Med        ISSN: 1971-3282


  27 in total

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2.  Maternal and perinatal outcome after expectant management of the HELLP syndrome compared with pre-eclampsia without HELLP syndrome.

Authors:  M G van Pampus; H Wolf; S M Westenberg; J A van der Post; G J Bonsel; P E Treffers
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  1998-01       Impact factor: 2.435

3.  Postpartum eclampsia: a recurring perinatal dilemma.

Authors:  J F Miles; J N Martin; P G Blake; K G Perry; R W Martin; G R Meeks
Journal:  Obstet Gynecol       Date:  1990-09       Impact factor: 7.661

4.  Neonatal salvage by week's gestation in pregnancies complicated by HELLP syndrome.

Authors:  E F Magann; K G Perry; S P Chauhan; G R Graves; P G Blake; J N Martin
Journal:  J Soc Gynecol Investig       Date:  1994 Jul-Sep

5.  HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome versus severe preeclampsia: onset at < or =28.0 weeks' gestation.

Authors:  B Haddad; J R Barton; J C Livingston; R Chahine; B M Sibai
Journal:  Am J Obstet Gynecol       Date:  2000-12       Impact factor: 8.661

6.  Neonatal outcome after preterm delivery in HELLP syndrome.

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7.  Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension in pregnancy.

Authors:  L Weinstein
Journal:  Am J Obstet Gynecol       Date:  1982-01-15       Impact factor: 8.661

8.  The HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): much ado about nothing?

Authors:  B M Sibai
Journal:  Am J Obstet Gynecol       Date:  1990-02       Impact factor: 8.661

Review 9.  Expectant management in pregnancies with severe pre-eclampsia.

Authors:  Bassam Haddad; Baha M Sibai
Journal:  Semin Perinatol       Date:  2009-06       Impact factor: 3.300

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Authors:  D Abramovici; S A Friedman; B M Mercer; F Audibert; L Kao; B M Sibai
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2.  Severe Preeclampsia versus HELLP Syndrome: Maternal and Perinatal Outcomes at <34 and ≥34 Weeks' Gestation.

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4.  Effect of HELLP syndrome on acute kidney injury in pregnancy and pregnancy outcomes: a systematic review and meta-analysis.

Authors:  Qiang Liu; Guan-Jun Ling; Shao-Quan Zhang; Wen-Qing Zhai; Yi-Juan Chen
Journal:  BMC Pregnancy Childbirth       Date:  2020-10-30       Impact factor: 3.007

5.  Incidence, characteristics, maternal complications, and perinatal outcomes associated with preeclampsia with severe features and HELLP syndrome.

Authors:  Kiattisak Kongwattanakul; Piyamas Saksiriwuttho; Sukanya Chaiyarach; Kaewjai Thepsuthammarat
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