Literature DB >> 22439041

Prenatal diagnosis of left isomerism with normal heart: a case report.

Nico De Paola1, Santina Ermito, Antonella Nahom, Angela Dinatale, Elisa Maria Pappalardo, Sabina Carrara, Alessandro Cavaliere, Cristiana Brizzi.   

Abstract

OBJECTIVE: Left isomerism, also called polysplenia, is a laterality disturbance associated with with paired leftsidedness viscera and multiple small spleens. Left isomerism, heart congenital abnormalities and gastrointestinal malformation are strongly associated.
METHODS: We present a case of prenatal diagnosis of left isomerism in a fetus with a structurally normal heart.
CONCLUSION: Left isomerism syndrone may coesist with a structurally normal heart. If prenatal left isomerism is suspected, even in presence of a normal heart, is mandatory to esclude sign of gastrointestinal abnormalities, as late poly hy dramnios, and cardiac rhytm disturbance during the pregnancy and neonatal age.

Entities:  

Keywords:  gut malrotation; left isomerism; normal heart; right sided stomach

Year:  2009        PMID: 22439041      PMCID: PMC3279108     

Source DB:  PubMed          Journal:  J Prenat Med        ISSN: 1971-3282


  11 in total

1.  Fetal echocardiographic evaluation of atrial morphology and the prediction of laterality in cases of heterotaxy syndromes.

Authors:  C Berg; A Geipel; T Kohl; J Smrcek; U Germer; A A Baschat; M Hansmann; U Gembruch
Journal:  Ultrasound Obstet Gynecol       Date:  2005-10       Impact factor: 7.299

2.  Isomerism of the atrial appendages in the fetus.

Authors:  S Y Ho; A Cook; R H Anderson; L D Allan; N Fagg
Journal:  Pediatr Pathol       Date:  1991 Jul-Aug

3.  Situs anomalies and gastrointestinal abnormalities.

Authors:  Seung Eun Lee; Hyun-Young Kim; Sung-Eun Jung; Seong-Cheol Lee; Kwi-Won Park; Woo-Ki Kim
Journal:  J Pediatr Surg       Date:  2006-07       Impact factor: 2.545

4.  Outcomes of left atrial isomerism over a 28-year period at a single institution.

Authors:  T Gilljam; B W McCrindle; J F Smallhorn; W G Williams; R M Freedom
Journal:  J Am Coll Cardiol       Date:  2000-09       Impact factor: 24.094

5.  The syndrome of left isomerism: sonographic findings and outcome in prenatally diagnosed cases.

Authors:  Christoph Berg; Annegret Geipel; Daniel Kamil; Mareike Knüppel; Johannes Breuer; Martin Krapp; Ahmet Baschat; Ute Germer; Manfred Hansmann; Ulrich Gembruch
Journal:  J Ultrasound Med       Date:  2005-07       Impact factor: 2.153

6.  Polysplenia: a review of 146 cases.

Authors:  W M Peoples; J H Moller; J E Edwards
Journal:  Pediatr Cardiol       Date:  1983 Apr-Jun       Impact factor: 1.655

7.  Characteristics and natural history of abnormal atrial rhythms in left isomerism.

Authors:  K Momma; A Takao; T Shibata
Journal:  Am J Cardiol       Date:  1990-01-15       Impact factor: 2.778

8.  Intrauterine diagnosis of heterotaxy syndrome.

Authors:  Jiuann-Huey Lin; Chang-I Chang; Jou-Kou Wang; Mei-Hwan Wu; Ming-Kwang Shyu; Chien-Nan Lee; Hung-Chi Lue; Fon-Chiou Hsieh
Journal:  Am Heart J       Date:  2002-06       Impact factor: 4.749

9.  Spectrum of cardiovascular disease, accuracy of diagnosis, and outcome in fetal heterotaxy syndrome.

Authors:  Mio Taketazu; Jane Lougheed; Shi-Joon Yoo; Joyce S L Lim; Lisa K Hornberger
Journal:  Am J Cardiol       Date:  2006-01-11       Impact factor: 2.778

10.  Prenatal diagnosis of cardiosplenic syndromes: a 10-year experience.

Authors:  C Berg; A Geipel; J Smrcek; M Krapp; U Germer; T Kohl; U Gembruch; A A Baschat
Journal:  Ultrasound Obstet Gynecol       Date:  2003-11       Impact factor: 7.299

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  2 in total

1.  Antenatal ultrasound diagnosis of small bowel non-rotation in complex left isomerism: a case report.

Authors:  Charles Arcus; Usha Sennaiyan; Amit Trivedi; Thushari I Alahakoon
Journal:  Int J Surg Case Rep       Date:  2019-02-19

2.  A novel DNAH11 variant segregating in a sibship with heterotaxy and implications for genetic counseling.

Authors:  Amirpouyan Namavarian; Anas Eid; Elaine Suk-Ying Goh; Varsha Thakur
Journal:  Mol Genet Genomic Med       Date:  2020-07-07       Impact factor: 2.183

  2 in total

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