Literature DB >> 22438317

Photoluminescent biocompatible silicon nanoparticles for cancer theranostic applications.

Liubov A Osminkina1, Konstantin P Tamarov, Andrey P Sviridov, Rostislav A Galkin, Maxim B Gongalsky, Valery V Solovyev, Andrey A Kudryavtsev, Victor Yu Timoshenko.   

Abstract

Silicon nanoparticles (SiNPs) obtained by mechanical grinding of porous silicon have been used for visualization of living cells in vitro. It was found that SiNPs could penetrate into the cells without any cytotoxic effect up to the concentration of 100 μg/ml. The cell cytoplasm was observed to be filled by SiNPs, which exhibited bright photoluminescence at 1.6 eV. SiNPs could also act as photosensitizers of the singlet oxygen generation, which could be used in the photodynamic therapy of cancer. These properties of SiNPs are discussed in view of possible applications in theranostics (both in therapy and in diagnostics).
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 22438317     DOI： 10.1002/jbio.201100112

Source DB:  PubMed          Journal:  J Biophotonics        ISSN： 1864-063X            Impact factor:   3.207


  10 in total

1.  Developing hyperpolarized silicon particles for in vivo MRI targeting of ovarian cancer.

Authors:  Nicholas Whiting; Jingzhe Hu; Niki M Zacharias; Ganesh L R Lokesh; David E Volk; David G Menter; Rajesha Rupaimoole; Rebecca Previs; Anil K Sood; Pratip Bhattacharya
Journal:  J Med Imaging (Bellingham)       Date:  2016-08-10

2.  Enhanced photoluminescence of porous silicon nanoparticles coated by bioresorbable polymers.

Authors:  Maxim B Gongalsky; Alexander Yu Kharin; Liubov A Osminkina; Victor Yu Timoshenko; Jinyoung Jeong; Han Lee; Bong Hyun Chung
Journal:  Nanoscale Res Lett       Date:  2012-08-08       Impact factor: 4.703

3.  Precise and selective sensing of DNA-DNA hybridization by graphene/Si-nanowires diode-type biosensors.

Authors:  Jungkil Kim; Shin-Young Park; Sung Kim; Dae Hun Lee; Ju Hwan Kim; Jong Min Kim; Hee Kang; Joong-Soo Han; Jun Woo Park; Hosun Lee; Suk-Ho Choi
Journal:  Sci Rep       Date:  2016-08-18       Impact factor: 4.379

4.  Radio frequency radiation-induced hyperthermia using Si nanoparticle-based sensitizers for mild cancer therapy.

Authors:  Konstantin P Tamarov; Liubov A Osminkina; Sergey V Zinovyev; Ksenia A Maximova; Julia V Kargina; Maxim B Gongalsky; Yury Ryabchikov; Ahmed Al-Kattan; Andrey P Sviridov; Marc Sentis; Andrey V Ivanov; Vladimir N Nikiforov; Andrei V Kabashin; Victor Yu Timoshenko
Journal:  Sci Rep       Date:  2014-11-13       Impact factor: 4.379

5.  Highly photostable nanogels for fluorescence-based theranostics.

Authors:  Dipendra Gyawali; Jimin P Kim; Jian Yang
Journal:  Bioact Mater       Date:  2017-03-27

6.  Raman and fluorescence micro-spectroscopy applied for the monitoring of sunitinib-loaded porous silicon nanocontainers in cardiac cells.

Authors:  E Tolstik; M B Gongalsky; J Dierks; T Brand; M Pernecker; N V Pervushin; D E Maksutova; K A Gonchar; J V Samsonova; G Kopeina; V Sivakov; L A Osminkina; K Lorenz
Journal:  Front Pharmacol       Date:  2022-08-09       Impact factor: 5.988

7.  Nanoparticles prepared from porous silicon nanowires for bio-imaging and sonodynamic therapy.

Authors:  Liubov A Osminkina; Vladimir A Sivakov; Grigory A Mysov; Veronika A Georgobiani; Ulyana А Natashina; Florian Talkenberg; Valery V Solovyev; Andrew A Kudryavtsev; Victor Yu Timoshenko
Journal:  Nanoscale Res Lett       Date:  2014-09-03       Impact factor: 4.703

8.  Linear and Non-Linear Optical Imaging of Cancer Cells with Silicon Nanoparticles.

Authors:  Elen Tolstik; Liubov A Osminkina; Denis Akimov; Maksim B Gongalsky; Andrew A Kudryavtsev; Victor Yu Timoshenko; Rainer Heintzmann; Vladimir Sivakov; Jürgen Popp
Journal:  Int J Mol Sci       Date:  2016-09-12       Impact factor: 5.923

9.  Nanoparticles Produced via Laser Ablation of Porous Silicon and Silicon Nanowires for Optical Bioimaging.

Authors:  Stanislav V Zabotnov; Anastasiia V Skobelkina; Ekaterina A Sergeeva; Daria A Kurakina; Aleksandr V Khilov; Fedor V Kashaev; Tatyana P Kaminskaya; Denis E Presnov; Pavel D Agrba; Dmitrii V Shuleiko; Pavel K Kashkarov; Leonid A Golovan; Mikhail Yu Kirillin
Journal:  Sensors (Basel)       Date:  2020-08-28       Impact factor: 3.576

Review 10.  Short-Pulse Lasers: A Versatile Tool in Creating Novel Nano-/Micro-Structures and Compositional Analysis for Healthcare and Wellbeing Challenges.

Authors:  Ahmed Al-Kattan; David Grojo; Christophe Drouet; Alexandros Mouskeftaras; Philippe Delaporte; Adrien Casanova; Jérôme D Robin; Frédérique Magdinier; Patricia Alloncle; Catalin Constantinescu; Vincent Motto-Ros; Jörg Hermann
Journal:  Nanomaterials (Basel)       Date:  2021-03-12       Impact factor: 5.076
  10 in total

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