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Literature DB >> 22438173

Fuzheng huayu capsule in the treatment of liver fibrosis: clinical evidence and mechanism of action.

Abstract

Liver fibrosis represents the wound healing response to liver injury from a wide variety of etiologies. Remarkable progresses have been shown in the field of liver fibrosis in a range of areas in the past years. In particular, the reversibility of liver fibrosis has been well documented in both patients and animal models. Great progresses have been made in the treatment of liver fibrosis with Chinese medicine. This review summarizes the effects of fuzheng huayu capsule (FZHYC) in treating liver fibrosis and inflammation induced by chronic hepatitis B in clinical trials and the mechanism of action of FZHYC in reversing liver fibrosis in vivo and in vitro experiments.

Entities: Disease Species

Mesh：

Substances：

Year: 2012 PMID： 22438173 DOI： 10.1007/s11655-012-1030-1

Source DB: PubMed Journal: Chin J Integr Med ISSN： 1672-0415 Impact factor: 1.978

8 in total

Review 1. Liver fibrosis -- from bench to bedside.

Authors: Scott L Friedman
Journal: J Hepatol Date: 2003 Impact factor: 25.083

2. Reversibility of hepatic fibrosis and cirrhosis--is it all hype?

Authors: Scott L Friedman
Journal: Nat Clin Pract Gastroenterol Hepatol Date: 2007-05

3. [Effect of fuzheng huayu recipe in treating posthepatitic cirrhosis].

Authors: P Liu; C Liu; Y Y Hu
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi Date: 1996-08

4. Multicenter clinical study on Fuzhenghuayu capsule against liver fibrosis due to chronic hepatitis B.

Authors: Ping Liu; Yi-Yang Hu; Cheng Liu; Lie-Ming Xu; Cheng-Hai Liu; Ke-Wei Sun; De-Chang Hu; You-Kuan Yin; Xia-Qiu Zhou; Mo-Bin Wan; Xiong Cai; Zhi-Qing Zhang; Jun Ye; Ren-Xing Zhou; Jia He; Bao-Zhang Tang
Journal: World J Gastroenterol Date: 2005-05-21 Impact factor: 5.742

5. [Serapharmacological effect of fuzheng huayu 319 Decoction on expression of type I collagen and transforming growth factor beta 1 in hepatic stellate cells].

Authors: C Liu; X Wang; P Liu
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi Date: 1999-07

6. Clinical observation of salvianolic acid B in treatment of liver fibrosis in chronic hepatitis B.

Authors: Ping Liu; Yi-Yang Hu; Cheng Liu; Da-Yuan Zhu; Hui-Ming Xue; Zhi-Qiang Xu; Lie-Ming Xu; Cheng-Hai Liu; Hong-Tu Gu; Zhi-Qing Zhang
Journal: World J Gastroenterol Date: 2002-08 Impact factor: 5.742

7. [The value of serum markers in evaluating liver fibrotic changes].

Authors: Yi-yang Hu; Ping Liu; Cheng Liu; Cheng-hai Liu; Lie-ming Xu
Journal: Zhonghua Gan Zang Bing Za Zhi Date: 2006-03

8. [Role of hepatic sinusoidal endothelium injury in hepatic fibrogenesis induced by dimethylnitrosamine in rats].

Authors: Xiong Lu; Ping Liu; Chenghai Liu; Guangfu Xu; Xianbo Wang; Wenhui Chen; Fenghua Li
Journal: Zhonghua Gan Zang Bing Za Zhi Date: 2002-12

8 in total

6 in total

1. A case of autoimmune hepatitis and primary biliary cirrhosis overlap syndrome treated with Chinese herbs.

Authors: Pan Zhao; Hao-zhen Yang; Jin-feng Li; Chun-ya Wang; Xin-Ying Liu; Yan-wei Zhong; Dong-ping Xu; Li Du; Shao-jie Xin
Journal: Chin J Integr Med Date: 2012-11-24 Impact factor: 1.978

Review 2. Pathogenesis of liver cirrhosis.

Authors: Wen-Ce Zhou; Quan-Bao Zhang; Liang Qiao
Journal: World J Gastroenterol Date: 2014-06-21 Impact factor: 5.742

6. Fuzheng Huayu Recipe Ameliorates Liver Fibrosis by Restoring Balance between Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Hepatic Stellate Cells.

Authors: Qin Pan; Yu-Qin Wang; Guang-Ming Li; Xiao-Yan Duan; Jian-Gao Fan
Journal: Biomed Res Int Date: 2015-12-31 Impact factor: 3.411