Literature DB >> 22438125

Inhalation study of polymethyl methacrylate following radiologist exposure during percutaneous vertebroplasty.

Nicolas Amoretti1, Lucia Coco, Yasir Nouri, Pierre-Yves Marcy, Antoine Ianessi, Marie-Eve Amoretti, Olivier Hauger.   

Abstract

OBJECTIVE: To assess the atmospheric concentrations of methyl methacrylate (MMA) vapors during percutaneous vertebroplasty for the interventional radiologist and the other operating room staff.
MATERIALS AND METHODS: During percutaneous vertebroplasty, a polymethyl methacrylate (PMMA) mixture (about 20 mL) was prepared with a mixing system in a normally ventilated room. Atmospheric concentrations of MMA vapors were measured by a gas absorbent badge for individual exposure (GABIE) passive sampler attached to the surgical gowns of the interventional radiologist and the other operating room staff over a period of 460 min. Active sampling was performed over 15 min with an individual pump placed near the breathing zone of the radiologist. MMA vapor concentrations were then measured using gas chromatography and activated charcoal tubes.
RESULTS: Mean MMA vapor concentrations measured by the GABIEs over the period of 460 min were 0.51 parts per million (ppm) for the radiologist and 0.22 ppm for the other operating room staff. The emission peaks measured by using charcoal tubes over 15 min were 3.7 ppm.
CONCLUSION: MMA vapor concentrations during percutaneous vertebroplasty were well below the recommended maximum exposure of 100 ppm over the course of an 8-h workday.

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Year:  2012        PMID: 22438125     DOI: 10.1007/s00256-012-1370-0

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


  25 in total

1.  Percutaneous vertebroplasty for spinal metastases: complications.

Authors:  Héctor Manuel Barragán-Campos; Jean-Noël Vallée; Daouda Lo; Evelyne Cormier; Beatrix Jean; Michèle Rose; Pascal Astagneau; Jacques Chiras
Journal:  Radiology       Date:  2006-01       Impact factor: 11.105

2.  Chronic inhalation toxicity and oncogenicity of methyl methacrylate in rats and hamsters.

Authors:  L G Lomax; N D Krivanek; S R Frame
Journal:  Food Chem Toxicol       Date:  1997 Mar-Apr       Impact factor: 6.023

3.  Pre-packed vacuum bone cement mixing systems. A further step in reducing methylmethacrylate exposure in surgery.

Authors:  Ulf J Schlegel; Michael Sturm; Peer Eysel; Steffen J Breusch
Journal:  Ann Occup Hyg       Date:  2010-06-30

4.  In vivo assessment of methyl methacrylate metabolism and toxicity.

Authors:  Z Bereznowski
Journal:  Int J Biochem Cell Biol       Date:  1995-12       Impact factor: 5.085

5.  Occupational asthma due to methyl methacrylate and cyanoacrylates.

Authors:  S Lozewicz; A G Davison; A Hopkirk; P S Burge; D A Boldy; J F Riordan; D V McGivern; B W Platts; D Davies; A J Newman Taylor
Journal:  Thorax       Date:  1985-11       Impact factor: 9.139

6.  Use of polymer materials in dental clinics, case study.

Authors:  E C Lönnroth; H Shahnavaz
Journal:  Swed Dent J       Date:  1997

7.  Efficacy of vacuum bone cement mixing systems in reducing methylmethacrylate fume exposure: comparison of 7 different mixing devices and handmixing.

Authors:  Ulf J Schlegel; Michael Sturm; Volker Ewerbeck; Steffen J Breusch
Journal:  Acta Orthop Scand       Date:  2004-10

8.  Two-year inhalation carcinogenesis studies of methyl methacrylate in rats and mice: inflammation and degeneration of nasal epithelium.

Authors:  P C Chan; S L Eustis; J E Huff; J K Haseman; H Ragan
Journal:  Toxicology       Date:  1988-11-30       Impact factor: 4.221

9.  Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up.

Authors:  A Cotten; F Dewatre; B Cortet; R Assaker; D Leblond; B Duquesnoy; P Chastanet; J Clarisse
Journal:  Radiology       Date:  1996-08       Impact factor: 11.105

10.  [Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty].

Authors:  P Galibert; H Deramond; P Rosat; D Le Gars
Journal:  Neurochirurgie       Date:  1987       Impact factor: 1.553

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  1 in total

Review 1.  Vertebroplasty in patients with tumour-related vertebral fractures: is rehabilitation needed?

Authors:  Massimiliano Polastri; Alessandro Gasbarrini
Journal:  Asian Spine J       Date:  2013-09-04
  1 in total

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