Electron-transfer processes in dendrimers and their implication in biology, catalysis, sensing and nanotechnology.

The extraordinary development of the design and synthesis of dendrimers has allowed scientists to locate redox sites at precise positions (core, focal points, branching points, termini, cavities) of these perfectly defined macromolecules, which have generation-controlled sizes and topologies matching those of biomolecules. Redox-dendrimer engineering has led to fine modelling studies of electron-transfer metalloproteins, in which the branches of the dendrimers hinder access to the active site in a manner reminiscent of that of the protein. It has also enabled the construction of remarkable catalysts, sensors and printboards, including by sophisticated design of the interface between redox dendrimers and solid-state devices - for example by functionalizing electrodes and other surfaces. Electron-transfer processes between dendrimers and a variety of other molecules hold promising applications in diverse areas that range from bio-engineering to sensing, catalysis and energy materials.