BACKGROUND: : The authors examined parameters of cardiovascular function using Starfish and deep pericardial sutures (DPS) in a beating heart porcine model and to clarify toleration of right ventricular function with Starfish in lateral wall displacement. METHODS: : Eight healthy pigs were used. In addition to normal pressure monitor catheters, a Swan-Ganz continuous cardiac output (CO) and end diastolic volume thermodilution catheter was used for precise and quantitative monitoring of the right ventricular function. RESULTS: : Lateral displacement of the heart with DPS resulted in a significant hemodynamic compromise. Cardiac output and right ventricular ejection fraction (RVEF) decreased from 3.0 ± 0.9 to 2.6 ± 1.0 L/min (P = 0.014) and from 27.9 ± 3.0% to 23.3 ± 4.8% (P = 0.019). With Starfish™, CO and RVEF were maintained from 3.0 ± 0.9 to 3.0 ± 0.9 L/min (P = 0.743) and from 27.9 ± 3.0% to 28.3 ± 3.8% (P = 0.476). CONCLUSION: : Starfish™ contributed to the stability of hemodynamics by maintaining the right ventricular function. Lateral displacement with PDS resulted in significant hemodynamic compromised compared with Starfish™ and baseline neutral position.
BACKGROUND: : The authors examined parameters of cardiovascular function using Starfish and deep pericardial sutures (DPS) in a beating heart porcine model and to clarify toleration of right ventricular function with Starfish in lateral wall displacement. METHODS: : Eight healthy pigs were used. In addition to normal pressure monitor catheters, a Swan-Ganz continuous cardiac output (CO) and end diastolic volume thermodilution catheter was used for precise and quantitative monitoring of the right ventricular function. RESULTS: : Lateral displacement of the heart with DPS resulted in a significant hemodynamic compromise. Cardiac output and right ventricular ejection fraction (RVEF) decreased from 3.0 ± 0.9 to 2.6 ± 1.0 L/min (P = 0.014) and from 27.9 ± 3.0% to 23.3 ± 4.8% (P = 0.019). With Starfish™, CO and RVEF were maintained from 3.0 ± 0.9 to 3.0 ± 0.9 L/min (P = 0.743) and from 27.9 ± 3.0% to 28.3 ± 3.8% (P = 0.476). CONCLUSION: : Starfish™ contributed to the stability of hemodynamics by maintaining the right ventricular function. Lateral displacement with PDS resulted in significant hemodynamic compromised compared with Starfish™ and baseline neutral position.