Literature DB >> 22435375

Lowering plasma cholesterol by raising LDL receptors--revisited.

Stephen G Young, Loren G Fong.   

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Year:  2012        PMID： 22435375      PMCID： PMC5611813          DOI： 10.1056/NEJMe1202168

Source DB:  PubMed          Journal:  N Engl J Med        ISSN： 0028-4793            Impact factor:   91.245


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  10 in total

1.  Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.

Authors:  Jonathan C Cohen; Eric Boerwinkle; Thomas H Mosley; Helen H Hobbs
Journal:  N Engl J Med       Date:  2006-03-23       Impact factor: 91.245

2.  Effect of a monoclonal antibody to PCSK9 on LDL cholesterol.

Authors:  Evan A Stein; Scott Mellis; George D Yancopoulos; Neil Stahl; Douglas Logan; William B Smith; Eleanor Lisbon; Maria Gutierrez; Cheryle Webb; Richard Wu; Yunling Du; Therese Kranz; Evelyn Gasparino; Gary D Swergold
Journal:  N Engl J Med       Date:  2012-03-22       Impact factor: 91.245

3.  Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

Authors:  Jonathan Cohen; Alexander Pertsemlidis; Ingrid K Kotowski; Randall Graham; Christine Kim Garcia; Helen H Hobbs
Journal:  Nat Genet       Date:  2005-01-16       Impact factor: 38.330

4.  Lowering plasma cholesterol by raising LDL receptors.

Authors:  M S Brown; J L Goldstein
Journal:  N Engl J Med       Date:  1981-08-27       Impact factor: 91.245

5.  Effect of an inhibitor of 3-hydroxy-3-methyglutaryl coenzyme A reductase on serum lipoproteins and ubiquinone-10-levels in patients with familial hypercholesterolemia.

Authors:  H Mabuchi; T Haba; R Tatami; S Miyamoto; Y Sakai; T Wakasugi; A Watanabe; J Koizumi; R Takeda
Journal:  N Engl J Med       Date:  1981-08-27       Impact factor: 91.245

6.  Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice.

Authors:  Thomas A Lagace; David E Curtis; Rita Garuti; Markey C McNutt; Sahng Wook Park; Heidi B Prather; Norma N Anderson; Y K Ho; Robert E Hammer; Jay D Horton
Journal:  J Clin Invest       Date:  2006-11       Impact factor: 14.808

7.  Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.

Authors:  Marianne Abifadel; Mathilde Varret; Jean-Pierre Rabès; Delphine Allard; Khadija Ouguerram; Martine Devillers; Corinne Cruaud; Suzanne Benjannet; Louise Wickham; Danièle Erlich; Aurélie Derré; Ludovic Villéger; Michel Farnier; Isabel Beucler; Eric Bruckert; Jean Chambaz; Bernard Chanu; Jean-Michel Lecerf; Gerald Luc; Philippe Moulin; Jean Weissenbach; Annick Prat; Michel Krempf; Claudine Junien; Nabil G Seidah; Catherine Boileau
Journal:  Nat Genet       Date:  2003-06       Impact factor: 38.330

8.  A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.

Authors:  Joyce C Y Chan; Derek E Piper; Qiong Cao; Dongming Liu; Chadwick King; Wei Wang; Jie Tang; Qiang Liu; Jared Higbee; Zhen Xia; Yongmei Di; Susan Shetterly; Ziva Arimura; Heather Salomonis; William G Romanow; Stephen T Thibault; Richard Zhang; Ping Cao; Xiao-Ping Yang; Timothy Yu; Mei Lu; Marc W Retter; Gayle Kwon; Kirk Henne; Oscar Pan; Mei-Mei Tsai; Bryna Fuchslocher; Evelyn Yang; Lei Zhou; Ki Jeong Lee; Mark Daris; Jackie Sheng; Yan Wang; Wenyan D Shen; Wen-Chen Yeh; Maurice Emery; Nigel P C Walker; Bei Shan; Margrit Schwarz; Simon M Jackson
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-14       Impact factor: 11.205

9.  PCSK9: a convertase that coordinates LDL catabolism.

Authors:  Jay D Horton; Jonathan C Cohen; Helen H Hobbs
Journal:  J Lipid Res       Date:  2008-11-19       Impact factor: 5.922

10.  LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor.

Authors:  Noam Zelcer; Cynthia Hong; Rima Boyadjian; Peter Tontonoz
Journal:  Science       Date:  2009-06-11       Impact factor: 47.728
  10 in total
  5 in total

Review 1.  A century of cholesterol and coronaries: from plaques to genes to statins.

Authors:  Joseph L Goldstein; Michael S Brown
Journal:  Cell       Date:  2015-03-26       Impact factor: 41.582

2.  The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice.

Authors:  Cynthia Hong; Stephanie M Marshall; Allison L McDaniel; Mark Graham; Joseph D Layne; Lei Cai; Elena Scotti; Rima Boyadjian; Jason Kim; Brian T Chamberlain; Rajendra K Tangirala; Michael E Jung; Loren Fong; Richard Lee; Stephen G Young; Ryan E Temel; Peter Tontonoz
Journal:  Cell Metab       Date:  2014-11-04       Impact factor: 27.287

3.  Severe hypertriglyceridemia as a cause of necrotizing pancreatitis in a pediatric patient with familial hyperchylomicronemia syndrome: A case report.

Authors:  Laura Valenzuela-Vallejo; Daniela Meléndrez-Vásquez; Paola Durán-Ventura; Carolina Rivera-Nieto; Adriana Lema; Monica Fernandez
Journal:  SAGE Open Med Case Rep       Date:  2022-07-07

Review 4.  Half a Century Tales of Familial Hypercholesterolemia (FH) in Japan.

Authors:  Hiroshi Mabuchi
Journal:  J Atheroscler Thromb       Date:  2017-02-08       Impact factor: 4.928

Review 5.  Pharmacogenetics of Statin-Induced Myotoxicity.

Authors:  Ping Siu Kee; Paul Ken Leong Chin; Martin A Kennedy; Simran D S Maggo
Journal:  Front Genet       Date:  2020-10-16       Impact factor: 4.599
  5 in total

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