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Literature DB >> 22433782

Local delivery of nitric oxide: targeted delivery of therapeutics to bone and connective tissues.

Scott P Nichols¹, Wesley L Storm, Ahyeon Koh, Mark H Schoenfisch.

Abstract

Non-invasive treatment of injuries and disorders affecting bone and connective tissue remains a significant challenge facing the medical community. A treatment route that has recently been proposed is nitric oxide (NO) therapy. Nitric oxide plays several important roles in physiology with many conditions lacking adequate levels of NO. As NO is a radical, localized delivery via NO donors is essential to promoting biological activity. Herein, we review current literature related to therapeutic NO delivery in the treatment of bone, skin and tendon repair.

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Year: 2012 PMID： 22433782 PMCID： PMC3383916 DOI： 10.1016/j.addr.2012.03.002

Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470

158 in total

Review 1. Cutaneous wound healing.

Authors: A J Singer; R A Clark
Journal: N Engl J Med Date: 1999-09-02 Impact factor: 91.245

2. The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium.

Authors: M W Radomski; R M Palmer; S Moncada
Journal: Biochem Biophys Res Commun Date: 1987-11-13 Impact factor: 3.575

Review 3. The biology of burn injury.

Authors: Lars H Evers; Dhaval Bhavsar; Peter Mailänder
Journal: Exp Dermatol Date: 2010-07-14 Impact factor: 3.960

Review 4. Reducing implant-related infections: active release strategies.

Authors: Evan M Hetrick; Mark H Schoenfisch
Journal: Chem Soc Rev Date: 2006-05-05 Impact factor: 54.564

5. Is nitroglycerin a novel and inexpensive treatment for osteoporosis?

Authors: Sundeep Khosla
Journal: JAMA Date: 2011-02-23 Impact factor: 56.272

6. "NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms.

Authors: L K Keefer; R W Nims; K M Davies; D A Wink
Journal: Methods Enzymol Date: 1996 Impact factor: 1.600

7. Inorganic/Organic Hybrid Silica Nanoparticles as a Nitric Oxide Delivery Scaffold.

Authors: Jae Ho Shin; Mark H Schoenfisch
Journal: Chem Mater Date: 2008-01-01 Impact factor: 9.811

8. The role of iNOS in wound healing.

Authors: H P Shi; D Most; D T Efron; U Tantry; M H Fischel; A Barbul
Journal: Surgery Date: 2001-08 Impact factor: 3.982

9. Nitric oxide enhances osteoclastogenesis possibly by mediating cell fusion.

Authors: Dorrin Nilforoushan; Azza Gramoun; Michael Glogauer; Morris F Manolson
Journal: Nitric Oxide Date: 2009-04-21 Impact factor: 4.427

10. Addition of nitric oxide through nitric oxide-paracetamol enhances healing rat achilles tendon.

Authors: George A C Murrell; Gongyao Tang; Richard C Appleyard; Piero del Soldato; Min-Xia Wang
Journal: Clin Orthop Relat Res Date: 2008-05-08 Impact factor: 4.176

26 in total

Review 1. Combination of nitric oxide and drug delivery systems: tools for overcoming drug resistance in chemotherapy.

Authors: Jihoon Kim; Bryant C Yung; Won Jong Kim; Xiaoyuan Chen
Journal: J Control Release Date: 2016-12-26 Impact factor: 9.776

2. Nitric oxide-releasing xerogels synthesized from N-diazeniumdiolate-modified silane precursors.

Authors: Wesley L Storm; Mark H Schoenfisch
Journal: ACS Appl Mater Interfaces Date: 2013-05-20 Impact factor: 9.229

3. Low-level laser irradiation stimulates tenocyte proliferation in association with increased NO synthesis and upregulation of PCNA and cyclins.

Authors: Wen-Chung Tsai; Ju-Wen Cheng; Jean-Lon Chen; Chen-Yin Chen; Hsiang-Ning Chang; Yu-Hsin Liao; Miao-Sui Lin; Jong-Hwei S Pang
Journal: Lasers Med Sci Date: 2014-02-09 Impact factor: 3.161

Local delivery of nitric oxide: targeted delivery of therapeutics to bone and connective tissues.

Review 1. Cutaneous wound healing.

2. The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium.

Review 3. The biology of burn injury.

Review 4. Reducing implant-related infections: active release strategies.

5. Is nitroglycerin a novel and inexpensive treatment for osteoporosis?

6. "NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms.

7. Inorganic/Organic Hybrid Silica Nanoparticles as a Nitric Oxide Delivery Scaffold.

8. The role of iNOS in wound healing.

9. Nitric oxide enhances osteoclastogenesis possibly by mediating cell fusion.

10. Addition of nitric oxide through nitric oxide-paracetamol enhances healing rat achilles tendon.

Review 1. Combination of nitric oxide and drug delivery systems: tools for overcoming drug resistance in chemotherapy.

2. Nitric oxide-releasing xerogels synthesized from N-diazeniumdiolate-modified silane precursors.

3. Low-level laser irradiation stimulates tenocyte proliferation in association with increased NO synthesis and upregulation of PCNA and cyclins.

4. Nitric oxide-releasing dendrimers as antibacterial agents.

5. S-Nitrosothiol-modified nitric oxide-releasing chitosan oligosaccharides as antibacterial agents.

6. Controlled release of nitric oxide from liposomes.

Review 7. Nitric Oxide-Releasing Macromolecular Scaffolds for Antibacterial Applications.

8. Inaccuracies of nitric oxide measurement methods in biological media.

9. Nitric oxide-releasing amphiphilic poly(amidoamine) (PAMAM) dendrimers as antibacterial agents.

10. Nitric oxide-releasing chitosan oligosaccharides as antibacterial agents.