| Literature DB >> 22433430 |
Anna Colpo1, Frederick H Wilson, Valentina Nardi, Ephraim Hochberg.
Abstract
Chemotherapy-induced peripheral neurotoxicity is a major problem because it represents the dose-limiting side effect of a significant number of antineoplastic drugs, such as vinca alkaloids. Hereditary neuropathies usually predispose to severe vincristine neurotoxicity. Here, we report the case of a 56-year-old man with Machado-Joseph disease, also known as spinocerebellar ataxia type 3, treated with a vinca alkaloid without exacerbation of neurological symptoms.Entities:
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Year: 2012 PMID: 22433430 PMCID: PMC3701890 DOI: 10.1159/000336602
Source DB: PubMed Journal: Oncology ISSN: 0030-2414 Impact factor: 2.935