Literature DB >> 22433281

JETTA: junction and exon toolkits for transcriptome analysis.

Junhee Seok1, Weihong Xu, Hong Gao, Ronald W Davis, Wenzhong Xiao.   

Abstract

SUMMARY: High-throughput genome-wide studies of alternatively spliced mRNA transcripts have become increasingly important in clinical research. Consequently, easy-to-use software tools are required to process data from these studies, for example, using exon and junction arrays. Here, we introduce JETTA, an integrated software package for the calculation of gene expression indices as well as the identification and visualization of alternative splicing events. We demonstrate the software using data of human liver and muscle samples hybridized on an exon-junction array. AVAILABILITY: JETTA and its demonstrations are freely available at http://igenomed.stanford.edu/~junhee/JETTA/index.html

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Year:  2012        PMID: 22433281      PMCID: PMC3338022          DOI: 10.1093/bioinformatics/bts134

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


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