| Literature DB >> 22430084 |
Steven Trifilio1, Irene Helenowski, Meghan Giel, Barbara Gobel, Judy Pi, Deborah Greenberg, Jayesh Mehta.
Abstract
The use of a neutropenic diet (ND) after hematopoietic stem cell transplantation (HSCT) was instituted more than 30 years ago as a means of preventing infection from organisms colonizing the gastrointestinal tract. Evidence supporting this practice is lacking, however, and the actual efficacy of the ND remains unknown. Institutional policy at Northwestern Memorial Hospital discontinued the use of ND in 2006. We conducted a retrospective study of 726 consecutive HSCT recipients, 363 who received an ND and 363 who received a general hospital diet, to determine the incidence of microbiologically confirmed infections during and after transplantation. Our findings indicate a higher rate of infections in the HSCT recipients who received an ND.Entities:
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Year: 2012 PMID： 22430084 DOI： 10.1016/j.bbmt.2012.02.015
Source DB: PubMed Journal: Biol Blood Marrow Transplant ISSN： 1083-8791 Impact factor: 5.742