Literature DB >> 22429337

Helical assembly in the death domain (DD) superfamily.

Ryan Ferrao1, Hao Wu.   

Abstract

Death domain (DD) superfamily members play a central role in apoptotic and inflammatory signaling through formation of oligomeric molecular scaffolds. These scaffolds promote the activation of proinflammatory and apoptotic initiator caspases, as well as Ser/Thr kinases. Interactions between DDs are facilitated by a conserved set of interaction surfaces, type I, type II, and type III. Recently structural information on a ternary complex containing the DDs of MyD88, IRAK4, and IRAK2 and a binary complex containing Fas and FADD DDs has become available. This review will focus on how the three DD interaction surfaces cooperate to facilitate the assembly of these oligomeric signaling complexes.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22429337      PMCID： PMC3320699          DOI： 10.1016/j.sbi.2012.02.006

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  33 in total

1.  A docking model of key components of the DISC complex: death domain superfamily interactions redefined.

Authors:  C H Weber; C Vincenz
Journal:  FEBS Lett       Date:  2001-03-16       Impact factor: 4.124

2.  Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling.

Authors:  D E Vaughn; J Rodriguez; Y Lazebnik; L Joshua-Tor
Journal:  J Mol Biol       Date:  1999-10-29       Impact factor: 5.469

3.  The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress.

Authors:  Antoine Tinel; Jürg Tschopp
Journal:  Science       Date:  2004-04-08       Impact factor: 47.728

4.  FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.

Authors:  A M Chinnaiyan; K O'Rourke; M Tewari; V M Dixit
Journal:  Cell       Date:  1995-05-19       Impact factor: 41.582

5.  Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.

Authors:  D Kägi; F Vignaux; B Ledermann; K Bürki; V Depraetere; S Nagata; H Hengartner; P Golstein
Journal:  Science       Date:  1994-07-22       Impact factor: 47.728

6.  Crystal structure of NALP3 protein pyrin domain (PYD) and its implications in inflammasome assembly.

Authors:  Ju Young Bae; Hyun Ho Park
Journal:  J Biol Chem       Date:  2011-08-31       Impact factor: 5.157

Review 7.  IRAK-4 as the central TIR signaling mediator in innate immunity.

Authors:  Nobutaka Suzuki; Shinobu Suzuki; Wen-Chen Yeh
Journal:  Trends Immunol       Date:  2002-10       Impact factor: 16.687

8.  The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition.

Authors:  Edvards Liepinsh; Raitis Barbals; Edgar Dahl; Anatoly Sharipo; Eike Staub; Gottfried Otting
Journal:  J Mol Biol       Date:  2003-10-03       Impact factor: 5.469

Review 9.  Toll-like receptors.

Authors:  Kiyoshi Takeda; Tsuneyasu Kaisho; Shizuo Akira
Journal:  Annu Rev Immunol       Date:  2001-12-19       Impact factor: 28.527

10.  NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain.

Authors:  Sebastian Hiller; Andreas Kohl; Francesco Fiorito; Torsten Herrmann; Gerhard Wider; Jürg Tschopp; Markus G Grütter; Kurt Wüthrich
Journal:  Structure       Date:  2003-10       Impact factor: 5.006
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  71 in total

Review 1.  Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily.

Authors:  Ryan Ferrao; Jixi Li; Elisa Bergamin; Hao Wu
Journal:  Sci Signal       Date:  2012-05-29       Impact factor: 8.192

Review 2.  Structural basis of signal transduction in the TNF receptor superfamily.

Authors:  Jixi Li; Qian Yin; Hao Wu
Journal:  Adv Immunol       Date:  2013       Impact factor: 3.543

3.  Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein.

Authors:  Tengchuan Jin; Mo Huang; Patrick Smith; Jiansheng Jiang; T Sam Xiao
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2013-07-27

4.  Crystal structure of the F27G AIM2 PYD mutant and similarities of its self-association to DED/DED interactions.

Authors:  Alvin Lu; Venkataraman Kabaleeswaran; Tianmin Fu; Venkat Giri Magupalli; Hao Wu
Journal:  J Mol Biol       Date:  2014-01-07       Impact factor: 5.469

Review 5.  Prion-like polymerization as a signaling mechanism.

Authors:  Xin Cai; Zhijian J Chen
Journal:  Trends Immunol       Date:  2014-11-12       Impact factor: 16.687

6.  Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome.

Authors:  Qi Hu; Di Wu; Wen Chen; Zhen Yan; Chuangye Yan; Tianxi He; Qionglin Liang; Yigong Shi
Journal:  Proc Natl Acad Sci U S A       Date:  2014-10-13       Impact factor: 11.205

7.  Molecular mechanism for NLRP6 inflammasome assembly and activation.

Authors:  Chen Shen; Alvin Lu; Wen Jun Xie; Jianbin Ruan; Roberto Negro; Edward H Egelman; Tian-Min Fu; Hao Wu
Journal:  Proc Natl Acad Sci U S A       Date:  2019-01-23       Impact factor: 11.205

8.  Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.

Authors:  Yang Li; Tian-Min Fu; Alvin Lu; Kristen Witt; Jianbin Ruan; Chen Shen; Hao Wu
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-02       Impact factor: 11.205

9.  Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein.

Authors:  Parimala R Vajjhala; Ruth E Mirams; Justine M Hill
Journal:  J Biol Chem       Date:  2012-10-12       Impact factor: 5.157

Review 10.  Molecular basis of NF-κB signaling.

Authors:  Johanna Napetschnig; Hao Wu
Journal:  Annu Rev Biophys       Date:  2013-03-11       Impact factor: 12.981
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