Literature DB >> 22426191

Neurodegeneration: Recall sugars, forget Alzheimer's.

Tony Lefebvre.   

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Year:  2012        PMID: 22426191     DOI: 10.1038/nchembio.920

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN: 1552-4450            Impact factor:   15.040


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  8 in total

1.  Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein.

Authors:  J Lewis; E McGowan; J Rockwood; H Melrose; P Nacharaju; M Van Slegtenhorst; K Gwinn-Hardy; M Paul Murphy; M Baker; X Yu; K Duff; J Hardy; A Corral; W L Lin; S H Yen; D W Dickson; P Davies; M Hutton
Journal:  Nat Genet       Date:  2000-08       Impact factor: 38.330

2.  Evidence of a balance between phosphorylation and O-GlcNAc glycosylation of Tau proteins--a role in nuclear localization.

Authors:  Tony Lefebvre; Stéphanie Ferreira; Laetitia Dupont-Wallois; Thierry Bussière; Marie-Joëlle Dupire; André Delacourte; Jean-Claude Michalski; Marie-Laure Caillet-Boudin
Journal:  Biochim Biophys Acta       Date:  2003-01-20

3.  A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo.

Authors:  Scott A Yuzwa; Matthew S Macauley; Julia E Heinonen; Xiaoyang Shan; Rebecca J Dennis; Yuan He; Garrett E Whitworth; Keith A Stubbs; Ernest J McEachern; Gideon J Davies; David J Vocadlo
Journal:  Nat Chem Biol       Date:  2008-06-29       Impact factor: 15.040

4.  Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation.

Authors:  Scott A Yuzwa; Xiaoyang Shan; Matthew S Macauley; Thomas Clark; Yuliya Skorobogatko; Keith Vosseller; David J Vocadlo
Journal:  Nat Chem Biol       Date:  2012-02-26       Impact factor: 15.040

Review 5.  Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus: a missing link to therapeutic potential.

Authors:  Naoyuki Sato; Shuko Takeda; Kozue Uchio-Yamada; Hironori Ueda; Tomomi Fujisawa; Hiromi Rakugi; Ryuichi Morishita
Journal:  Curr Aging Sci       Date:  2011-07

Review 6.  From tau phosphorylation to tau aggregation: what about neuronal death?

Authors:  Luc Buée; Laëtitia Troquier; Sylvie Burnouf; Karim Belarbi; Anneke Van der Jeugd; Tariq Ahmed; Francisco Fernandez-Gomez; Raphaelle Caillierez; Marie-Eve Grosjean; Séverine Begard; Bérangère Barbot; Dominique Demeyer; Hélène Obriot; Ingrid Brion; Valérie Buée-Scherrer; Claude-Alain Maurage; Detlef Balschun; Rudi D'hooge; Malika Hamdane; David Blum; Nicolas Sergeant
Journal:  Biochem Soc Trans       Date:  2010-08       Impact factor: 5.407

7.  Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

Authors:  Eric Steen; Benjamin M Terry; Enrique J Rivera; Jennifer L Cannon; Thomas R Neely; Rose Tavares; X Julia Xu; Jack R Wands; Suzanne M de la Monte
Journal:  J Alzheimers Dis       Date:  2005-02       Impact factor: 4.472

8.  O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.

Authors:  Fei Liu; Khalid Iqbal; Inge Grundke-Iqbal; Gerald W Hart; Cheng-Xin Gong
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-12       Impact factor: 11.205

  8 in total
  1 in total

1.  Inhibition of O-GlcNAcase (OGA): A Potential Therapeutic Target to Treat Alzheimer's Disease.

Authors:  Ahmed F Abdel-Magid
Journal:  ACS Med Chem Lett       Date:  2014-11-20       Impact factor: 4.345

  1 in total

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