Literature DB >> 22425214

Anatomical surgical planning for oral and oropharyngeal primary carcinoma combined with adjuvant treatment where indicated is associated with improved local control.

Jeremy D McMahon1, John C Devine, Ling Siew Wong, Craig Wales, Miller Smith, Alan James, Ravi Jampana, Douglas McLellan.   

Abstract

We aimed to find out whether surgical tactics that lead to a reduction in tumour-involved surgical margins also improve local control. We retrospectively reviewed a consecutive case series (n=162) of previously untreated patients who had operations for squamous cell carcinoma (SCC) of the oral cavity or oropharynx. Extensive use was made of computed tomographic multiplanar imaging to plan primary resections. Nine patients (6%) had tumour at the resection margin. Local control at 36 months was 96%, disease-specific survival (DSS) was 86%, and overall survival (OS) was 77%. Carefully planned primary operation for SCC of the oral cavity and oropharynx to minimise tumour-involved margins combined with conventional adjuvant treatment where indicated, is associated with a high probability of local control and disease-specific survival.
Copyright © 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 22425214     DOI: 10.1016/j.bjoms.2012.02.009

Source DB:  PubMed          Journal:  Br J Oral Maxillofac Surg        ISSN: 0266-4356            Impact factor:   1.651


  1 in total

1.  Assessment of cervical lymph node metastasis for therapeutic decision-making in squamous cell carcinoma of buccal mucosa: a prospective clinical analysis.

Authors:  Harald Essig; Riaz Warraich; Gulraiz Zulfiqar; Madiha Rana; André Michael Eckardt; Nils-Claudius Gellrich; Majeed Rana
Journal:  World J Surg Oncol       Date:  2012-11-22       Impact factor: 2.754

  1 in total

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