| Literature DB >> 22424219 |
Louis M Weiner1, Joseph C Murray, Casey W Shuptrine.
Abstract
By targeting surface antigens expressed on tumor cells, monoclonal antibodies have demonstrated efficacy as cancer therapeutics. Recent successful antibody-based strategies have focused on enhancing antitumor immune responses by targeting immune cells, irrespective of tumor antigens. We discuss these innovative strategies and propose how they will impact the future of antibody-based cancer therapy.Entities:
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Year: 2012 PMID: 22424219 PMCID: PMC3310896 DOI: 10.1016/j.cell.2012.02.034
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582