Literature DB >> 22423961

Crossing the Rubicon: new roads lead to host defense.

Clinton J Bradfield1, Bae-Hoon Kim, John D MacMicking.   

Abstract

Rubicon is a protein known to engage the Beclin-1/Vps34-PI3K/UVRAG complex and inhibit endosome and autophagosomal fusion with lysosomes. Yang et al. (2012) uncover new roles for this adaptor protein within noncanonical p22(phox) or CARD9 complexes that regulate oxidative and cytokine responses in activated macrophages, respectively. Both complexes impact pathogen-specific host defense. Copyright Â
© 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22423961      PMCID： PMC3859237          DOI： 10.1016/j.chom.2012.02.005

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN： 1931-3128            Impact factor:   21.023


  11 in total

1.  Rubicon controls endosome maturation as a Rab7 effector.

Authors:  Qiming Sun; Wiebke Westphal; Kwun Ngok Wong; Irena Tan; Qing Zhong
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-25       Impact factor: 11.205

2.  Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity.

Authors:  Olaf Gross; Andreas Gewies; Katrin Finger; Martin Schäfer; Tim Sparwasser; Christian Peschel; Irmgard Förster; Jürgen Ruland
Journal:  Nature       Date:  2006-07-12       Impact factor: 49.962

3.  Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages.

Authors:  Kohichi Matsunaga; Tatsuya Saitoh; Keisuke Tabata; Hiroko Omori; Takashi Satoh; Naoki Kurotori; Ikuko Maejima; Kanae Shirahama-Noda; Tohru Ichimura; Toshiaki Isobe; Shizuo Akira; Takeshi Noda; Tamotsu Yoshimori
Journal:  Nat Cell Biol       Date:  2009-03-08       Impact factor: 28.824

4.  Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.

Authors:  Chul-Su Yang; Jong-Soo Lee; Mary Rodgers; Chan-Ki Min; June-Yong Lee; Hee Jin Kim; Kwang-Hoon Lee; Chul-Joong Kim; Byungha Oh; Ebrahim Zandi; Zhenyu Yue; Igor Kramnik; Chengyu Liang; Jae U Jung
Journal:  Cell Host Microbe       Date:  2012-03-15       Impact factor: 21.023

Review 5.  Disease tolerance as a defense strategy.

Authors:  Ruslan Medzhitov; David S Schneider; Miguel P Soares
Journal:  Science       Date:  2012-02-24       Impact factor: 47.728

6.  Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome.

Authors:  Sonja I Gringhuis; Tanja M Kaptein; Brigitte A Wevers; Bart Theelen; Michiel van der Vlist; Teun Boekhout; Teunis B H Geijtenbeek
Journal:  Nat Immunol       Date:  2012-01-22       Impact factor: 25.606

Review 7.  Secretory products of macrophages.

Authors:  C F Nathan
Journal:  J Clin Invest       Date:  1987-02       Impact factor: 14.808

8.  A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.

Authors:  Bae-Hoon Kim; Avinash R Shenoy; Pradeep Kumar; Rituparna Das; Sangeeta Tiwari; John D MacMicking
Journal:  Science       Date:  2011-05-06       Impact factor: 47.728

9.  Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.

Authors:  Yun Zhong; Qing Jun Wang; Xianting Li; Ying Yan; Jonathan M Backer; Brian T Chait; Nathaniel Heintz; Zhenyu Yue
Journal:  Nat Cell Biol       Date:  2009-03-08       Impact factor: 28.824

10.  Recognizing macrophage activation and host defense.

Authors:  John D MacMicking
Journal:  Cell Host Microbe       Date:  2009-05-08       Impact factor: 21.023
View more
  4 in total

1.  CARD9 knockout ameliorates myocardial dysfunction associated with high fat diet-induced obesity.

Authors:  Li Cao; Xing Qin; Matthew R Peterson; Samantha E Haller; Kayla A Wilson; Nan Hu; Xin Lin; Sreejayan Nair; Jun Ren; Guanglong He
Journal:  J Mol Cell Cardiol       Date:  2016-02-17       Impact factor: 5.000

Review 2.  Molecular and physiological roles of the adaptor protein CARD9 in immunity.

Authors:  Xiaoming Zhong; Bin Chen; Liang Yang; Zhiwen Yang
Journal:  Cell Death Dis       Date:  2018-01-19       Impact factor: 8.469

3.  Zinc rescues obesity-induced cardiac hypertrophy via stimulating metallothionein to suppress oxidative stress-activated BCL10/CARD9/p38 MAPK pathway.

Authors:  Shudong Wang; Junlian Gu; Zheng Xu; Zhiguo Zhang; Tao Bai; Jianxiang Xu; Jun Cai; Gregory Barnes; Qiu-Ju Liu; Jonathan H Freedman; Yonggang Wang; Quan Liu; Yang Zheng; Lu Cai
Journal:  J Cell Mol Med       Date:  2017-02-03       Impact factor: 5.310

Review 4.  Tripping on acid: trans-kingdom perspectives on biological acids in immunity and pathogenesis.

Authors:  Michael F Criscitiello; Martin B Dickman; James E Samuel; Paul de Figueiredo
Journal:  PLoS Pathog       Date:  2013-07-18       Impact factor: 6.823
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.