Literature DB >> 2242396

Barium sulphate-loaded p(HEMA) microspheres as artificial emboli: preparation and properties.

B C Thanoo1, A Jayakrishnan.   

Abstract

Poly(2-hydroxyethyl methacrylate) p(HEMA) microspheres of good spherical geometry (diameter 90-1500 microns) encapsulated with 40-50% barium sulphate to impart radiopaque properties were prepared by a solvent evaporation process. These microspheres were cross-linked by reacting with hexamethylene diisocyanate (HMDI) or by gamma-irradiation in the presence of ethylene glycol dimethacrylate (EGDM) in n-heptane. Microspheres with a porous structure and a rough surface were also made by the incorporation of NaCl along with BaSO4. The effects of concentration of the polymer solution, concentration of the stabilizing agent, concentration of BaSO4, viscosity of the dispersion medium and ratio of the dispersed phase to the dispersion medium on the formation, stability and particle size distribution of the microspheres were investigated.

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Year:  1990        PMID： 2242396     DOI： 10.1016/0142-9612(90)90061-t

Source DB:  PubMed          Journal:  Biomaterials        ISSN： 0142-9612            Impact factor:   12.479


  7 in total

Review 1.  Bench-to-clinic development of imageable drug-eluting embolization beads: finding the balance.

Authors:  Andrew L Lewis; Sean L Willis; Matthew R Dreher; Yiqing Tang; Koorosh Ashrafi; Bradford J Wood; Elliot B Levy; Karun V Sharma; Ayele H Negussie; Andrew S Mikhail
Journal:  Future Oncol       Date:  2018-06-26       Impact factor: 3.404

2.  Synthesis and characterization of image-able polyvinyl alcohol microspheres for image-guided chemoembolization.

Authors:  Ayele H Negussie; Matthew R Dreher; Carmen Gacchina Johnson; Yiqing Tang; Andrew L Lewis; Gert Storm; Karun V Sharma; Bradford J Wood
Journal:  J Mater Sci Mater Med       Date:  2015-06-24       Impact factor: 3.896

3.  Studies on novel radiopaque methyl methacrylate: glycidyl methacrylate based polymer for biomedical applications.

Authors:  S Dawlee; A Jayakrishnan; M Jayabalan
Journal:  J Mater Sci Mater Med       Date:  2008-07-31       Impact factor: 3.896

4.  Preliminary investigation of the dissolution behavior, cytocompatibility, effects of fibrinogen conformation and platelet adhesion for radiopaque embolic particles.

Authors:  Sharon Kehoe; Marie-Laurence Tremblay; Aisling Coughlan; Mark R Towler; Jan K Rainey; Robert J Abraham; Daniel Boyd
Journal:  J Funct Biomater       Date:  2013-07-10

5.  A Novel Inherently Radiopaque Bead for Transarterial Embolization to Treat Liver Cancer - A Pre-clinical Study.

Authors:  Rafael Duran; Karun Sharma; Matthew R Dreher; Koorosh Ashrafi; Sahar Mirpour; MingDe Lin; Ruediger E Schernthaner; Todd R Schlachter; Vania Tacher; Andrew L Lewis; Sean Willis; Mark den Hartog; Alessandro Radaelli; Ayele H Negussie; Bradford J Wood; Jean-François H Geschwind
Journal:  Theranostics       Date:  2016-01-01       Impact factor: 11.556

6.  Radiopaque Hemocompatible Ruminant-Sourced Gut Material with Antimicrobial Physiognomies for Biomedical Applications in Diabetics.

Authors:  Nimmy K Francis; Harpreet S Pawar; Santanu Dhara; Anirban Mitra; Analava Mitra
Journal:  ACS Omega       Date:  2017-03-02

7.  Synthesis, characterization, and imaging of radiopaque bismuth beads for image-guided transarterial embolization.

Authors:  Ayele H Negussie; Quirina M B de Ruiter; Hugh Britton; Danielle R Donahue; Quentin Boffi; Young-Seung Kim; William F Pritchard; Chrit Moonen; Gert Storm; Andrew L Lewis; Bradford J Wood
Journal:  Sci Rep       Date:  2021-01-12       Impact factor: 4.996
  7 in total

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