Literature DB >> 22422673

Palladium-catalyzed carbonylative Heck reaction of aryl bromides with vinyl ethers to 3-alkoxy alkenones and pyrazoles.

Johannes Schranck1, Xiao-Feng Wu, Helfried Neumann, Matthias Beller.   

Abstract

Three COming together: The first carbonylative Heck coupling reaction of aryl bromides and vinyl ethers leading to 1-aryl-3-alkoxy-2-propen-1-ones has been established (see scheme). Based on this coupling methodology, a novel one-pot synthesis of aryl-substituted pyrazoles was also realized.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Year:  2012        PMID: 22422673     DOI: 10.1002/chem.201103643

Source DB:  PubMed          Journal:  Chemistry        ISSN: 0947-6539            Impact factor:   5.236


  1 in total

1.  Hydroxylated chalcones with dual properties: Xanthine oxidase inhibitors and radical scavengers.

Authors:  Emily Hofmann; Jonathan Webster; Thuy Do; Reid Kline; Lindsey Snider; Quintin Hauser; Grace Higginbottom; Austin Campbell; Lili Ma; Stefan Paula
Journal:  Bioorg Med Chem       Date:  2015-12-17       Impact factor: 3.641

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.