Aalia Akber1, Anthony A Portale, Kirsten L Johansen. 1. Department of Pediatrics, Division of Pediatric Nephrology, University of California, San Francisco, San Francisco, California, USA.
Abstract
BACKGROUND AND OBJECTIVES: Data on physical activity are limited in children with CKD. The objectives of this study were to measure the level and correlates of physical activity in children and young adults with CKD and to determine the association of physical activity with physical performance and physical functioning. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Physical activity was measured for 7 days using pedometers; physical performance was measured by the 6-minute walk distance (6MWD) and physical functioning with the PedsQL 4.0. RESULTS: Study participants were 44 patients 7-20 years of age who had CKD stage 1-4 (n=12), had ESRD and were undergoing dialysis (n=7), or had undergone kidney transplantation (n=25). Participants were very sedentary; they walked 6218 (interquartile range, 3637, 9829) steps per day, considerably less than recommended. Physical activity did not differ among participants in the CKD stage 1-4, ESRD, and transplant groups. Females were less active than males (P<0.01), and physical activity was 44% lower among young adults (18-20 years) than younger participants (P<0.05). Physical activity was associated positively with maternal education and hemoglobin concentration and inversely with body mass index. Respective 6MWD in males and females was 2 and approximately 4 SDs below expected. Low levels of physical activity were associated with poor physical performance and physical functioning, after adjustment for age, sex, and body mass index. CONCLUSIONS: In most participants with CKD, physical activity was considerably below recommended levels. Future studies are needed to determine whether increasing physical activity can improve physical performance and physical functioning.
BACKGROUND AND OBJECTIVES: Data on physical activity are limited in children with CKD. The objectives of this study were to measure the level and correlates of physical activity in children and young adults with CKD and to determine the association of physical activity with physical performance and physical functioning. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Physical activity was measured for 7 days using pedometers; physical performance was measured by the 6-minute walk distance (6MWD) and physical functioning with the PedsQL 4.0. RESULTS: Study participants were 44 patients 7-20 years of age who had CKD stage 1-4 (n=12), had ESRD and were undergoing dialysis (n=7), or had undergone kidney transplantation (n=25). Participants were very sedentary; they walked 6218 (interquartile range, 3637, 9829) steps per day, considerably less than recommended. Physical activity did not differ among participants in the CKD stage 1-4, ESRD, and transplant groups. Females were less active than males (P<0.01), and physical activity was 44% lower among young adults (18-20 years) than younger participants (P<0.05). Physical activity was associated positively with maternal education and hemoglobin concentration and inversely with body mass index. Respective 6MWD in males and females was 2 and approximately 4 SDs below expected. Low levels of physical activity were associated with poor physical performance and physical functioning, after adjustment for age, sex, and body mass index. CONCLUSIONS: In most participants with CKD, physical activity was considerably below recommended levels. Future studies are needed to determine whether increasing physical activity can improve physical performance and physical functioning.
Authors: Amy Berrington de Gonzalez; Patricia Hartge; James R Cerhan; Alan J Flint; Lindsay Hannan; Robert J MacInnis; Steven C Moore; Geoffrey S Tobias; Hoda Anton-Culver; Laura Beane Freeman; W Lawrence Beeson; Sandra L Clipp; Dallas R English; Aaron R Folsom; D Michal Freedman; Graham Giles; Niclas Hakansson; Katherine D Henderson; Judith Hoffman-Bolton; Jane A Hoppin; Karen L Koenig; I-Min Lee; Martha S Linet; Yikyung Park; Gaia Pocobelli; Arthur Schatzkin; Howard D Sesso; Elisabete Weiderpass; Bradley J Willcox; Alicja Wolk; Anne Zeleniuch-Jacquotte; Walter C Willett; Michael J Thun Journal: N Engl J Med Date: 2010-12-02 Impact factor: 91.245
Authors: Kirsten L Johansen; Glenn M Chertow; Nancy G Kutner; Lorien S Dalrymple; Barbara A Grimes; George A Kaysen Journal: Kidney Int Date: 2010-09-01 Impact factor: 10.612
Authors: K L Johansen; G M Chertow; A V Ng; K Mulligan; S Carey; P Y Schoenfeld; J A Kent-Braun Journal: Kidney Int Date: 2000-06 Impact factor: 10.612
Authors: Emily R Berkman; Kelsey L Richardson; Jonna D Clark; André A S Dick; Mithya Lewis-Newby; Douglas S Diekema; Aaron G Wightman Journal: Pediatr Nephrol Date: 2022-04-29 Impact factor: 3.714
Authors: Keith K Lau; Joyce Obeid; Peter Breithaupt; Vladimir Belostotsky; Steven Arora; Thanh Nguyen; Brian W Timmons Journal: Pediatr Nephrol Date: 2014-10-10 Impact factor: 3.714
Authors: Nancy M Rodig; Jennifer Roem; Michael F Schneider; Patricia W Seo-Mayer; Kimberly J Reidy; Frederick J Kaskel; Amy J Kogon; Susan L Furth; Bradley A Warady Journal: Pediatr Nephrol Date: 2021-01-21 Impact factor: 3.714