| Literature DB >> 22422214 |
Alastair A Cant1, Rajiv Bhalla, Sally L Pimlott, Andrew Sutherland.
Abstract
A fast and efficient nickel-catalysed iodination reaction of aryl and heteroaryl bromides has been developed. The transformation was found to be general for a wide range of substrates and was used for the synthesis of iodo-PK11195, an imaging agent of Alzheimer's disease and iniparib, a compound used in the treatment of breast cancer.Entities:
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Year: 2012 PMID： 22422214 DOI： 10.1039/c2cc30956d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222