Literature DB >> 22422013

A water soluble Cu(I)-NHC for CuAAC ligation of unprotected peptides under open air conditions.

Christelle Gaulier1, Audrey Hospital, Bertrand Legeret, Agnès F Delmas, Vincent Aucagne, Federico Cisnetti, Arnaud Gautier.   

Abstract

A reducing agent-free version of CuAAC able to operate under open air conditions is reported. A readily-synthesizable, hydrophilic and highly stable Cu(I)-NHC allows the clean ligations of unprotected peptides comprising sensitive side chains, at millimolar concentrations.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22422013     DOI： 10.1039/c2cc30515a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  Click Chemistry and Radiochemistry: The First 10 Years.

Authors:  Jan-Philip Meyer; Pierre Adumeau; Jason S Lewis; Brian M Zeglis
Journal:  Bioconjug Chem       Date:  2016-11-22       Impact factor: 4.774

Review 2.  Recent Progress of Cu-Catalyzed Azide-Alkyne Cycloaddition Reactions (CuAAC) in Sustainable Solvents: Glycerol, Deep Eutectic Solvents, and Aqueous Media.

Authors:  Noel Nebra; Joaquín García-Álvarez
Journal:  Molecules       Date:  2020-04-26       Impact factor: 4.411

3.  Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) by Functionalized NHC-Based Polynuclear Catalysts: Scope and Mechanistic Insights.

Authors:  Miguel González-Lainez; Miguel Gallegos; Julen Munarriz; Ramón Azpiroz; Vincenzo Passarelli; M Victoria Jiménez; Jesús J Pérez-Torrente
Journal:  Organometallics       Date:  2022-07-15       Impact factor: 3.837

4.  Effective ascorbate-free and photolatent click reactions in water using a photoreducible copper(II)-ethylenediamine precatalyst.

Authors:  Redouane Beniazza; Natalia Bayo; Florian Molton; Carole Duboc; Stéphane Massip; Nathan McClenaghan; Dominique Lastécouères; Jean-Marc Vincent
Journal:  Beilstein J Org Chem       Date:  2015-10-21       Impact factor: 2.883
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.