| Literature DB >> 22420949 |
Verena Lammel1, Christina Stoeckle, Barbara Padberg, Roland Zweifel, Dirk L Kienle, Walter H Reinhart, Hans-Uwe Simon.
Abstract
In contrast to leukocytosis, paraneoplastic hypereosinophilia is uncommon in lung cancer. We present a patient with large-cell carcinoma of the lung, in which cancer cells generate large amounts of GM-CSF leading to a leukemoid reaction with prominent hypereosinophilia and potentially involved in autocrine tumor stimulation.Entities:
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Year: 2012 PMID： 22420949 DOI： 10.1016/j.lungcan.2012.02.014
Source DB: PubMed Journal: Lung Cancer ISSN： 0169-5002 Impact factor: 5.705