CONTEXT: Hematological manifestations are less known in primary hyperparathyroidism (PHPT). Anemia has been recognized as a complication of PHPT in 5-30% of the individuals in various series. OBJECTIVE: Our objective was to identify hematological improvement after the curative parathyroidectomy in a PHPT patient with anemia and thrombocytopenia. PATIENT AND METHODS: A 30-yr-old female presented with recurrent renal stone disease, anemia, and thrombocytopenia diagnosed as PHPT. Bone marrow examination revealed megakaryocytic thrombocytopenia. Two months after the curative parathyroidectomy, her symptoms and hematological parameters were improved. CONCLUSION: Our finding showed a causal association of both anemia and thrombocytopenia with marrow fibrosis in a symptomatic PHPT patient because both anemia and thrombocytopenia improved after the curative parathyroidectomy.
CONTEXT: Hematological manifestations are less known in primary hyperparathyroidism (PHPT). Anemia has been recognized as a complication of PHPT in 5-30% of the individuals in various series. OBJECTIVE: Our objective was to identify hematological improvement after the curative parathyroidectomy in a PHPT patient with anemia and thrombocytopenia. PATIENT AND METHODS: A 30-yr-old female presented with recurrent renal stone disease, anemia, and thrombocytopenia diagnosed as PHPT. Bone marrow examination revealed megakaryocytic thrombocytopenia. Two months after the curative parathyroidectomy, her symptoms and hematological parameters were improved. CONCLUSION: Our finding showed a causal association of both anemia and thrombocytopenia with marrow fibrosis in a symptomatic PHPT patient because both anemia and thrombocytopenia improved after the curative parathyroidectomy.
Authors: Steven De Keukeleire; Kristoff Muylle; Georgios Tsoumalis; Stefan Vermeulen; Dirk Vogelaers Journal: Clin Cases Miner Bone Metab Date: 2017-05-30
Authors: Remya Rajan; Immanuel Paul; Kripa Elizabeth Cherian; Anu Korula; Julie Hephzibah; Marie Therese Manipadam; Deepak Thomas Abraham; Nitin Kapoor; Thomas Vizhalil Paul Journal: AACE Clin Case Rep Date: 2020-12-28