Colleen Rivard1, Alia Salhadar, Kimberly Kenton. 1. Department of Obstetrics and Gynecology, Loyola University Medical Center, Maywood, IL 60153, USA. crivardhunt@gmail.com
Abstract
STUDY OBJECTIVE: To evaluate the accuracy in diagnosing endometrial disease after uterine morcellation. DESIGN: Prospective case series. SETTING: University medical center. PATIENTS: Five women undergoing hysterectomy without morcellation because of benign indications and 5 women with endometrial cancer. INTERVENTIONS: Uterine specimens were obtained from all 10 study patients. The uteri were sent for pathologic analysis, processed, and fixed according to standard protocols. A single investigator then morcellated all 10 uteri. A single pathologist blinded to specimen group reviewed each specimen. MAIN RESULTS: The pathologist identified endometrial cancer in 4 of 5 specimens of known cancer. The fifth specimen was interpreted as benign despite the presence of grade 1, stage IA endometrial adenocarcinoma. None of the morcellated specimens could be staged. CONCLUSION: The increasing use of uterine morcellation will result in new challenges for gynecologic oncologists secondary to difficulty in detection, and accurate grading and staging of endometrial cancer.
STUDY OBJECTIVE: To evaluate the accuracy in diagnosing endometrial disease after uterine morcellation. DESIGN: Prospective case series. SETTING: University medical center. PATIENTS: Five women undergoing hysterectomy without morcellation because of benign indications and 5 women with endometrial cancer. INTERVENTIONS: Uterine specimens were obtained from all 10 study patients. The uteri were sent for pathologic analysis, processed, and fixed according to standard protocols. A single investigator then morcellated all 10 uteri. A single pathologist blinded to specimen group reviewed each specimen. MAIN RESULTS: The pathologist identified endometrial cancer in 4 of 5 specimens of known cancer. The fifth specimen was interpreted as benign despite the presence of grade 1, stage IA endometrial adenocarcinoma. None of the morcellated specimens could be staged. CONCLUSION: The increasing use of uterine morcellation will result in new challenges for gynecologic oncologists secondary to difficulty in detection, and accurate grading and staging of endometrial cancer.
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