Literature DB >> 22417864

Clonality in gynecologic neoplasms: is it time to reevaluate clonality studies in gynecologic neoplasms? Is it possible to confirm multicentricity with clonality studies?

Elvio G Silva1, Xavier Matias-Guiu.   

Abstract

This article reviews issues with clonality applied to gynecologic neoplasms. It is our opinion that the current interpretation of clonality studies in gynecologic neoplasms needs to be reevaluated because multicentricity, probably a common mechanism of tumor development in gynecology, cannot be confirmed with clonality.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22417864     DOI： 10.1016/j.anndiagpath.2012.01.007

Source DB:  PubMed          Journal:  Ann Diagn Pathol        ISSN： 1092-9134            Impact factor:   2.090


  1 in total

1.  Massively Parallel Sequencing-Based Clonality Analysis of Synchronous Endometrioid Endometrial and Ovarian Carcinomas.

Authors:  Anne M Schultheis; Charlotte K Y Ng; Maria R De Filippo; Salvatore Piscuoglio; Gabriel S Macedo; Sonia Gatius; Belen Perez Mies; Robert A Soslow; Raymond S Lim; Agnes Viale; Kety H Huberman; Jose C Palacios; Jorge S Reis-Filho; Xavier Matias-Guiu; Britta Weigelt
Journal:  J Natl Cancer Inst       Date:  2016-02-01       Impact factor: 13.506
  1 in total

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