| Literature DB >> 22415473 |
Kathryn Curran1, Jared M Baeten, Thomas J Coates, Ann Kurth, Nelly R Mugo, Connie Celum.
Abstract
A substantial proportion of HIV-1 infected individuals in sub-Saharan Africa are in stable relationships with HIV-1 uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling about risk reduction, and referrals to HIV-1 treatment, reproductive health services, and support services. Maximizing HIV-1 prevention for HIV-1 serodiscordant couples requires a combination of strategies, including counseling about condoms, sexual risk, fertility, contraception, and the clinical and prevention benefits of antiretroviral therapy (ART) for the HIV-1-infected partner; provision of clinical care and ART for the HIV-1-infected partner; antenatal care and services to prevent mother-to-child transmission for HIV-1-infected pregnant women; male circumcision for HIV-1-uninfected men; and, pending guidelines and demonstration projects, oral pre-exposure prophylaxis (PrEP) for HIV-1-uninfected partners.Entities:
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Year: 2012 PMID： 22415473 PMCID： PMC3570050 DOI： 10.1007/s11904-012-0114-z
Source DB: PubMed Journal: Curr HIV/AIDS Rep ISSN： 1548-3568 Impact factor: 5.071