PURPOSE: The aim of the study was to assess sentinel lymph node biopsy (SLNB) results in colon cancer (CC) regarding basic anthropometric features of the studied population and their derivatives calculated using mathematical formulas. METHODS: One hundred three SLNBs in CC have been analysed. Various indicators were calculated for every patient using mathematical formulas: BMI, Roher's index, lean body weight, body fat percentage and body weight/ideal body weight for a given height ratios using the following formulas: Broca's, Broca's ideal weight, Broca-Brugsch, Lorenz's, Potton's, Devine's, Robinson's, Miller's and Hamwi. The results were compared with accuracy, sensitivity and false negative results percentage by means of ROC curves and the test for structure indicators (for determined cut-off points). RESULTS: No statistically significant relationship between the results and patients' sex or age were found. ROC curve analysis did not reveal statistically significant relationships between the obtained results and indicators calculated on the basis of growth and weigh (all p > 0.05). The analyses of sensitivity and accuracy with determined cut-off point, in spite of differences amounting to 19 % (analysis of lean body weight/weight ratio), showed no statistical significance for any of the relationships (all p > 0.05). CONCLUSIONS: No indicator with high diagnostic and prognostic value has been found. The problem of qualifying patients for SLNB in CC in regard of the anthropometric features of the population and body composition assessment formulas remains open and requires further analysis on larger populations.
PURPOSE: The aim of the study was to assess sentinel lymph node biopsy (SLNB) results in colon cancer (CC) regarding basic anthropometric features of the studied population and their derivatives calculated using mathematical formulas. METHODS: One hundred three SLNBs in CC have been analysed. Various indicators were calculated for every patient using mathematical formulas: BMI, Roher's index, lean body weight, body fat percentage and body weight/ideal body weight for a given height ratios using the following formulas: Broca's, Broca's ideal weight, Broca-Brugsch, Lorenz's, Potton's, Devine's, Robinson's, Miller's and Hamwi. The results were compared with accuracy, sensitivity and false negative results percentage by means of ROC curves and the test for structure indicators (for determined cut-off points). RESULTS: No statistically significant relationship between the results and patients' sex or age were found. ROC curve analysis did not reveal statistically significant relationships between the obtained results and indicators calculated on the basis of growth and weigh (all p > 0.05). The analyses of sensitivity and accuracy with determined cut-off point, in spite of differences amounting to 19 % (analysis of lean body weight/weight ratio), showed no statistical significance for any of the relationships (all p > 0.05). CONCLUSIONS: No indicator with high diagnostic and prognostic value has been found. The problem of qualifying patients for SLNB in CC in regard of the anthropometric features of the population and body composition assessment formulas remains open and requires further analysis on larger populations.
Authors: Olivier Tiffet; David Kaczmarek; Marie Laure Chambonnière; Thomas Guillan; Sylviane Baccot; Nathalie Prévot; Sherban Bageacu; Eric Bourgeois; Elisabeth Cassagnau; Paul Antoine Lehur; Francis Dubois Journal: Dis Colon Rectum Date: 2007-07 Impact factor: 4.585
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Authors: Anton J Bilchik; Maggie DiNome; Sukamal Saha; Roderick R Turner; David Wiese; Martin McCarter; Dave S B Hoon; Donald L Morton Journal: Arch Surg Date: 2006-06
Authors: Andreas E Bembenek; Robert Rosenberg; Elke Wagler; Stephan Gretschel; Andreas Sendler; Joerg-Ruediger Siewert; Jörg Nährig; Helmut Witzigmann; Johann Hauss; Christian Knorr; Arno Dimmler; Jörn Gröne; Heinz-Johannes Buhr; Jörg Haier; Hermann Herbst; Juergen Tepel; Bence Siphos; Axel Kleespies; Alfred Koenigsrainer; Nikolas H Stoecklein; Olaf Horstmann; Robert Grützmann; Andreas Imdahl; Daniel Svoboda; Christian Wittekind; Wolfgang Schneider; Klaus-Dieter Wernecke; Peter M Schlag Journal: Ann Surg Date: 2007-06 Impact factor: 12.969
Authors: Gaëtan Des Guetz; Bernard Uzzan; Patrick Nicolas; Michel Cucherat; Philippe de Mestier; Jean-François Morere; Jean-Luc Breau; Gérard Perret Journal: World J Surg Date: 2007-06 Impact factor: 3.282