Literature DB >> 22414750

CTCF-dependent chromatin insulator as a built-in attenuator of angiogenesis.

Jianrong Lu1, Ming Tang.   

Abstract

VEGF is a pivotal pro-angiogenic growth factor and its dosage decisively impacts vascularization. We recently identified a CTCF-dependent chromatin insulator that critically restrains the transcriptional induction of VEGF and angiogenesis. We postulate that CTCF may exert enhancer blocking by mediating chromatin looping and/or RNA polymerase pausing at the VEGF locus.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22414750      PMCID： PMC3337828          DOI： 10.4161/trns.19634

Source DB:  PubMed          Journal:  Transcription        ISSN： 2154-1272


  34 in total

1.  Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity.

Authors:  Galina N Filippova; Chen-Feng Qi; Jonathan E Ulmer; James M Moore; Michael D Ward; Ying J Hu; Dmitri I Loukinov; Elena M Pugacheva; Elena M Klenova; Paul E Grundy; Andrew P Feinberg; Anne-Marie Cleton-Jansen; Elna W Moerland; Cees J Cornelisse; Hiroyoshi Suzuki; Akira Komiya; Annika Lindblom; Françoise Dorion-Bonnet; Paul E Neiman; Herbert C Morse; Steven J Collins; Victor V Lobanenkov
Journal:  Cancer Res       Date:  2002-01-01       Impact factor: 12.701

2.  Multiple nucleosome positioning sites regulate the CTCF-mediated insulator function of the H19 imprinting control region.

Authors:  Meena Kanduri; Chandrasekhar Kanduri; Piero Mariano; Alexander A Vostrov; Wolfgang Quitschke; Victor Lobanenkov; Rolf Ohlsson
Journal:  Mol Cell Biol       Date:  2002-05       Impact factor: 4.272

Review 3.  Insulators: exploiting transcriptional and epigenetic mechanisms.

Authors:  Miklos Gaszner; Gary Felsenfeld
Journal:  Nat Rev Genet       Date:  2006-08-15       Impact factor: 53.242

Review 4.  The role of insulator elements in defining domains of gene expression.

Authors:  P K Geyer
Journal:  Curr Opin Genet Dev       Date:  1997-04       Impact factor: 5.578

Review 5.  Enhancers: the abundance and function of regulatory sequences beyond promoters.

Authors:  Michael Bulger; Mark Groudine
Journal:  Dev Biol       Date:  2009-12-16       Impact factor: 3.582

Review 6.  Transcriptional regulation of vascular endothelial growth factor in cancer.

Authors:  Robyn M B Loureiro; Patricia A D'Amore
Journal:  Cytokine Growth Factor Rev       Date:  2005-02       Impact factor: 7.638

7.  Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.

Authors:  Wenqiang Yu; Vasudeva Ginjala; Vinod Pant; Igor Chernukhin; Joanne Whitehead; France Docquier; Dawn Farrar; Gholamreza Tavoosidana; Rituparna Mukhopadhyay; Chandrasekhar Kanduri; Mitsuo Oshimura; Andrew P Feinberg; Victor Lobanenkov; Elena Klenova; Rolf Ohlsson
Journal:  Nat Genet       Date:  2004-09-07       Impact factor: 38.330

8.  CTCF-mediated functional chromatin interactome in pluripotent cells.

Authors:  Lusy Handoko; Han Xu; Guoliang Li; Chew Yee Ngan; Elaine Chew; Marie Schnapp; Charlie Wah Heng Lee; Chaopeng Ye; Joanne Lim Hui Ping; Fabianus Mulawadi; Eleanor Wong; Jianpeng Sheng; Yubo Zhang; Thompson Poh; Chee Seng Chan; Galih Kunarso; Atif Shahab; Guillaume Bourque; Valere Cacheux-Rataboul; Wing-Kin Sung; Yijun Ruan; Chia-Lin Wei
Journal:  Nat Genet       Date:  2011-06-19       Impact factor: 38.330

9.  Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature.

Authors:  Andrew Scott; Michael B Powner; Pranita Gandhi; Claire Clarkin; David H Gutmann; Randall S Johnson; Napoleone Ferrara; Marcus Fruttiger
Journal:  PLoS One       Date:  2010-07-29       Impact factor: 3.240

10.  The relationship between transcription initiation RNAs and CCCTC-binding factor (CTCF) localization.

Authors:  Ryan J Taft; Peter G Hawkins; John S Mattick; Kevin V Morris
Journal:  Epigenetics Chromatin       Date:  2011-08-03       Impact factor: 4.954
View more
  6 in total

1.  Ribosomal RNA gene transcription mediated by the master genome regulator protein CCCTC-binding factor (CTCF) is negatively regulated by the condensin complex.

Authors:  Kaimeng Huang; Jinping Jia; Changwei Wu; Mingze Yao; Min Li; Jingji Jin; Cizhong Jiang; Yong Cai; Duanqing Pei; Guangjin Pan; Hongjie Yao
Journal:  J Biol Chem       Date:  2013-07-24       Impact factor: 5.157

2.  Adipose tissue derived stromal cells in a gelatin-based 3D matrix with exclusive ascorbic acid signalling emerged as a novel neural tissue engineering construct: an innovative prototype for soft tissue.

Authors:  Catherine Ann Martin; Subathra Radhakrishnan; Jose Luis Gómez Ribelles; Omana Anna Trentz; Nivethaa Eak; Mettu Srinivas Reddy; Mohamed Rela; Narayana Kalkura Subbaraya
Journal:  Regen Biomater       Date:  2022-05-24

3.  Promoter-proximal CCCTC-factor binding is associated with an increase in the transcriptional pausing index.

Authors:  Sur Herrera Paredes; Michael F Melgar; Praveen Sethupathy
Journal:  Bioinformatics       Date:  2012-10-09       Impact factor: 6.937

4.  Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue.

Authors:  David A Hill; Hee-Woong Lim; Yong Hoon Kim; Wesley Y Ho; Yee Hoon Foong; Victoria L Nelson; Hoang C B Nguyen; Kavya Chegireddy; Jihoon Kim; Andreas Habertheuer; Prashanth Vallabhajosyula; Taku Kambayashi; Kyoung-Jae Won; Mitchell A Lazar
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-14       Impact factor: 11.205

5.  The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells.

Authors:  Anna R Roy; Abdalla Ahmed; Peter V DiStefano; Lijun Chi; Nadiya Khyzha; Niels Galjart; Michael D Wilson; Jason E Fish; Paul Delgado-Olguín
Journal:  J Biol Chem       Date:  2018-04-02       Impact factor: 5.157

6.  TET-Catalyzed 5-Carboxylcytosine Promotes CTCF Binding to Suboptimal Sequences Genome-wide.

Authors:  Kyster K Nanan; David M Sturgill; Maria F Prigge; Morgan Thenoz; Allissa A Dillman; Mariana D Mandler; Shalini Oberdoerffer
Journal:  iScience       Date:  2019-07-30
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.