Literature DB >> 2241455

Lovastatin. Warfarin interaction.

S Ahmad1.   

Abstract

Two patients who developed hypoprothrombinemia and bleeding due to lovastatin-warfarin drug interaction are described. Because of the wider use of lovastatin and warfarin, heightened clinical awareness of this potentially serious interaction must be publicized. Therefore, prothrombin time should be monitored diligently when warfarin is prescribed to patients receiving lovastatin.

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Year:  1990        PMID: 2241455     DOI: 10.1001/archinte.150.11.2407

Source DB:  PubMed          Journal:  Arch Intern Med        ISSN: 0003-9926


  14 in total

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Review 3.  Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors.

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4.  Pharmacodynamic evaluation of warfarin and rosuvastatin co-administration in healthy subjects.

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Review 5.  How well tolerated are lipid-lowering drugs?

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Review 6.  Fluvastatin: a review of its pharmacology and use in the management of hypercholesterolaemia.

Authors:  G L Plosker; A J Wagstaff
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Review 7.  Antihyperlipidaemic agents. Drug interactions of clinical significance.

Authors:  J A Farmer; A M Gotto
Journal:  Drug Saf       Date:  1994-11       Impact factor: 5.606

Review 8.  Clinically significant drug interactions with the oral anticoagulants.

Authors:  M D Freedman; A G Olatidoye
Journal:  Drug Saf       Date:  1994-05       Impact factor: 5.606

Review 9.  Drug interactions of lipid-altering drugs.

Authors:  H E Bays; C A Dujovne
Journal:  Drug Saf       Date:  1998-11       Impact factor: 5.606

Review 10.  Pharmacogenetics of oral anticoagulants: a basis for dose individualization.

Authors:  Simone Stehle; Julia Kirchheiner; Andreas Lazar; Uwe Fuhr
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