Literature DB >> 22414472

Posterolateral spondylodesis using bioactive glass S53P4 and autogenous bone in instrumented unstable lumbar spine burst fractures. A prospective 10-year follow-up study.

J Rantakokko1, J P Frantzén, J Heinänen, S Kajander, E Kotilainen, E Gullichsen, N C Lindfors.   

Abstract

BACKGROUND AND AIMS: A prospective long-term follow-up study of bioactive glass (BAG)-S53P4 and autogenous bone (AB) used as bone graft substitutes for posterolateral spondylodesis in treatment of unstable lumbar spine burst fractures during 1996-1998 was conducted.
MATERIAL AND METHODS: The lumbar fractures were fixed using posterior USS instrumentation. BAG was implanted on the left side of the fusion-bed and AB on the right side. The operative outcome was evaluated on X-rays and CT scans, and a clinical examination was also performed.
RESULTS: The Oswestry score was excellent, and the mean pain score 1. The mean compression rate of the injured vertebral body was 25%. A solid bony fusion was seen on CT scans on the AB side in all patients and on the BAG side in five patients, and a partial fusion in five patients, resulting in a total fusion-rate of 71% of all fused segments in the BAG group.
CONCLUSIONS: Our long-term results show that BAG-S54P4 bone graft material is safe to be used as a bone graft extender in spine surgery.

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Year:  2012        PMID: 22414472     DOI: 10.1177/145749691210100113

Source DB:  PubMed          Journal:  Scand J Surg        ISSN: 1457-4969            Impact factor:   2.360


  8 in total

1.  Bioactive glass granules for mastoid and epitympanic surgical obliteration: CT and MRI appearance.

Authors:  Daniele Bernardeschi; Bruno Law-Ye; Franck Bielle; Baptiste Hochet; Olivier Sterkers; Didier Dormont; Nadya Pyatigorskaya
Journal:  Eur Radiol       Date:  2019-03-19       Impact factor: 5.315

2.  Clinical experience with the use of a spherical bioactive glass putty for cervical and lumbar interbody fusion.

Authors:  L Erik Westerlund; Mark Borden
Journal:  J Spine Surg       Date:  2020-03

Review 3.  [Application and research status of bioactive glass in bone repair].

Authors:  Yonghua Huang; Li Li; Zhanying Shi; Xu Cui; Haobo Pan; Bing Li
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2020-05-15

Review 4.  Recent Evidence on Bioactive Glass Antimicrobial and Antibiofilm Activity: A Mini-Review.

Authors:  Lorenzo Drago; Marco Toscano; Marta Bottagisio
Journal:  Materials (Basel)       Date:  2018-02-24       Impact factor: 3.623

5.  Clinical and radiographic outcomes using third-generation bioactive glass as a bone graft substitute for multi-level anterior cervical discectomy and fusion-a retrospective case series study.

Authors:  Gilberto Gomez; L Erik Westerlund
Journal:  J Spine Surg       Date:  2021-06

Review 6.  Clinical Applications of S53P4 Bioactive Glass in Bone Healing and Osteomyelitic Treatment: A Literature Review.

Authors:  N A P van Gestel; J Geurts; D J W Hulsen; B van Rietbergen; S Hofmann; J J Arts
Journal:  Biomed Res Int       Date:  2015-10-04       Impact factor: 3.411

Review 7.  Bioactive Glasses: Frontiers and Challenges.

Authors:  Larry L Hench; Julian R Jones
Journal:  Front Bioeng Biotechnol       Date:  2015-11-30

8.  Cutaneous and Labyrinthine Tolerance of Bioactive Glass S53P4 in Mastoid and Epitympanic Obliteration Surgery: Prospective Clinical Study.

Authors:  Daniele Bernardeschi; Yann Nguyen; Francesca Yoshie Russo; Isabelle Mosnier; Evelyne Ferrary; Olivier Sterkers
Journal:  Biomed Res Int       Date:  2015-10-04       Impact factor: 3.411

  8 in total

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