| Literature DB >> 22414335 |
Qingjian Ouyang1, Xiangyan Zhao, Haiping Feng, You Tian, Dan Li, Mingfu Li, Zhongyang Tan.
Abstract
The presence, locations and composition of simple sequence repeats (SSRs) in Herpes simplex virus type 1 (HSV-1) genome were extracted and analyzed by using the software Imperfect Microsatellite Extractor (IMEx). There were 663 mon-, 502 di-, 184 tri-, 20 tetra-, 4 penta- and 4 hexanucleotide SSRs that were observed in different distribution between coding and noncoding regions in the HSV-1 genome. G/C, GC/CG, and (GGC)(n) were predominant in mononucleotide, dinucletide, trinucleotide repeats respectively. Indeed, the results showed that GC content in simple sequence repeats was notably higher than that in entire HSV-1 genome. Our data might be helpful for studying the pathogenesis, genome structure and evolution of HSV-1.Entities:
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Year: 2012 PMID： 22414335 DOI： 10.1016/j.gene.2012.02.049
Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688