Literature DB >> 22413991

Molecular mechanisms of the PRL phosphatases.

Pablo Rios1, Xun Li, Maja Köhn.   

Abstract

The phosphatases of regenerating liver (PRLs) are an intriguing family of dual specificity phosphatases due to their oncogenicity. The three members are small, single domain enzymes. We provide an overview of the phosphatases of regenerating liver, compare them to related phosphatases, and review recent reports about each phosphatase. Finally, we discuss similarities and differences between the phosphatases of regenerating liver, focusing on their molecular mechanisms and signalling pathways.
© 2012 The Authors Journal compilation © 2012 FEBS.

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Year:  2012        PMID： 22413991     DOI： 10.1111/j.1742-4658.2012.08565.x

Source DB:  PubMed          Journal:  FEBS J        ISSN： 1742-464X            Impact factor:   5.542


  60 in total

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Review 4.  Protein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transduction.

Authors:  Nicholas K Tonks
Journal:  FEBS J       Date:  2013-01-17       Impact factor: 5.542

5.  Localizing PRL-2 expression and determining the effects of dietary Mg(2+) on expression levels.

Authors:  Jeremy Gungabeesoon; Michel L Tremblay; Noriko Uetani
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6.  Novel Anticancer Agents Based on Targeting the Trimer Interface of the PRL Phosphatase.

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Journal:  Cancer Res       Date:  2016-06-20       Impact factor: 12.701

7.  Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.

Authors:  Yosuke Funato; Daisuke Yamazaki; Shin Mizukami; Lisa Du; Kazuya Kikuchi; Hiroaki Miki
Journal:  J Clin Invest       Date:  2014-10-27       Impact factor: 14.808

8.  Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.

Authors:  Paula Giménez-Mascarell; Iker Oyenarte; Serge Hardy; Tilman Breiderhoff; Marchel Stuiver; Elie Kostantin; Tammo Diercks; Angel L Pey; June Ereño-Orbea; María Luz Martínez-Chantar; Reham Khalaf-Nazzal; Felix Claverie-Martin; Dominik Müller; Michel L Tremblay; Luis Alfonso Martínez-Cruz
Journal:  J Biol Chem       Date:  2016-11-29       Impact factor: 5.157

9.  Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.

Authors:  Michihiro Kobayashi; Sarah C Nabinger; Yunpeng Bai; Momoko Yoshimoto; Rui Gao; Sisi Chen; Chonghua Yao; Yuanshu Dong; Lujuan Zhang; Sonia Rodriguez; Yumi Yashiro-Ohtani; Warren S Pear; Nadia Carlesso; Mervin C Yoder; Reuben Kapur; Mark H Kaplan; Hugo Daniel Lacorazza; Zhong-Yin Zhang; Yan Liu
Journal:  Stem Cells       Date:  2017-01-19       Impact factor: 6.277

Review 10.  Phosphatase of regenerating liver in hematopoietic stem cells and hematological malignancies.

Authors:  Michihiro Kobayashi; Sisi Chen; Rui Gao; Yunpeng Bai; Zhong-Yin Zhang; Yan Liu
Journal:  Cell Cycle       Date:  2014       Impact factor: 4.534
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