Restraint of undomesticated animals.

The capture, by means of chemical immobilization, of about 100 large African animals of 17 different species was accomplished by use of compound M.99, an oripavine with morphine-like activity, but with approximately 1,000 times the activity of morphine. Usually, the compound was used in conjunction with a tranquilizer and scopolamine. The small dose required enabled M.99 to be administered by a projectile syringe of 2-ml. capacity. The effect of the immobilizing compound can be reversed with nalorphine or with compound M.285.