Literature DB >> 22409825

EBV-associated lymphomas in adults.

Mark Roschewski1, Wyndham H Wilson.   

Abstract

Epstein-Barr virus (EBV) is a ubiquitous γ-herpes virus that infects most people but results in life-threatening diseases in only a small subset. Persons who are unable to maintain the virus in its latent state can develop uncontrolled EBV-driven lymphoproliferative disorders and lymphomas. EBV-associated lymphomas are well characterized in patients with known defects in cellular immunity as occurs post-transplantation or HIV/AIDS but are increasingly recognized in patients without overt immunodeficiencies. Improved understanding of the biology of these lymphomas and the role EBV plays in lymphomagenesis offer the opportunity for improved therapies targeted at important signaling pathways and immunotherapy specific against EBV viral antigens. Published by Elsevier Ltd.

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Year:  2012        PMID： 22409825      PMCID： PMC3305910          DOI： 10.1016/j.beha.2012.01.005

Source DB:  PubMed          Journal:  Best Pract Res Clin Haematol        ISSN： 1521-6926            Impact factor:   3.020


  94 in total

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Review 6.  Post-transplantation lymphoproliferative disorders: diagnosis, prognosis, and current approaches to therapy.

Authors:  Andrew M Evens; Rupali Roy; Danielle Sterrenberg; Michelle Z Moll; Amy Chadburn; Leo I Gordon
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Journal:  Am J Transplant       Date:  2011-05       Impact factor: 8.086

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  19 in total

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Review 4.  Diagnosis and management of lymphomas and other cancers in HIV-infected patients.

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Review 5.  A review on EBV encoded and EBV-induced host microRNAs expression profile in different lymphoma types.

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6.  Long-Term Survival Rates of Patients with Stage III-IV Hodgkin Lymphoma According to Age, Sex, Race, and Socioeconomic Status, 1984-2013.

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7.  Spontaneous remission of chemo-immunotherapy related, non-transplant Epstein-Barr virus-associated lymphoproliferative disorder in a patient with chronic lymphocytic leukemia.

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8.  Diffuse large B-cell lymphoma in a South African cohort with a high HIV prevalence: an analysis by cell-of-origin, Epstein-Barr virus infection and survival.

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9.  Metagenomic detection of viruses in aerosol samples from workers in animal slaughterhouses.

Authors:  Richard J Hall; Mily Leblanc-Maridor; Jing Wang; Xiaoyun Ren; Nicole E Moore; Collin R Brooks; Matthew Peacey; Jeroen Douwes; David J McLean
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10.  Secondary Hemophagocytic Syndrome Associated with Richter's Transformation in Chronic Lymphocytic Leukemia.

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