Literature DB >> 22408150

Contact tracing in pulmonary and non-pulmonary tuberculosis.

P Mandal1, R Craxton, J D Chalmers, S Gilhooley, I F Laurenson, C McSparron, J Stevenson, A T Hill.   

Abstract

AIM: The aim of our study was to determine the effectiveness of contact tracing for both pulmonary and non-pulmonary tuberculosis (TB).
METHODS: The authors studied contact tracing in South East of Scotland, Edinburgh TB Clinic, UK, for 3 years. New index cases of both pulmonary and non-pulmonary TB were identified from reviewing TB nurses records. Pulmonary involvement was excluded from all non-pulmonary cases. Active TB was diagnosed as per the national TB guidelines. Latent TB was diagnosed based on history, tuberculin skin test and interferon γ release assay. TB contacts were identified from reviewing TB nurses notes on index TB patients. A positive screening episode was defined as identification of either active or latent TB in a contact following relevant investigations.
RESULTS: Total number of positive screening episodes for pulmonary TB was 43.1% and non-pulmonary TB was 26.1%. Of these, 78.8% were household contacts and 21.2% were casual contacts.
CONCLUSION: Contact tracing in low-prevalence TB countries, for both pulmonary and non-pulmonary TB, is an essential intervention to identify and reduce the number of infected patients that will progress to active disease. This is the key for effective TB control.

Entities:  

Mesh:

Year:  2012        PMID: 22408150     DOI: 10.1093/qjmed/hcs045

Source DB:  PubMed          Journal:  QJM        ISSN: 1460-2393


  3 in total

1.  An evaluation of tuberculosis contact investigations against national standards.

Authors:  Sean M Cavany; Tom Sumner; Emilia Vynnycky; Clare Flach; Richard G White; H Lucy Thomas; Helen Maguire; Charlotte Anderson
Journal:  Thorax       Date:  2017-04-07       Impact factor: 9.139

2.  High prevalence of TB disease in contacts of adults with extrapulmonary TB.

Authors:  Tom Wingfield; Peter MacPherson; Paul Cleary; L Peter Ormerod
Journal:  Thorax       Date:  2017-11-16       Impact factor: 9.139

3.  Latent Tuberculosis Infection Diagnostic and Treatment Cascade among Contacts in Primary Health Care in a City of Sao Paulo State, Brazil: Cross-Sectional Study.

Authors:  Anneliese Domingues Wysocki; Tereza Cristina Scatena Villa; Tiemi Arakawa; Maria Eugênia Firmino Brunello; Silvia Helena Figueiredo Vendramini; Aline Aparecida Monroe; Afranio Lineu Kritski
Journal:  PLoS One       Date:  2016-06-10       Impact factor: 3.240

  3 in total

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