| Literature DB >> 22407398 |
Anne-Sophie Bernard1, Claire Giroud, H Y Vincent Ching, Anne Meunier, Vinita Ambike, Christian Amatore, Manon Guille Collignon, Frédéric Lemaître, Clotilde Policar.
Abstract
SOD-mimics are small complexes that reproduce the activity of superoxide dismutases, natural proteins that catalytically dismutate the superoxide anion. Activated macrophages, which produce ROS and RNS fluxes, constitute a relevant model to challenge antioxidant activity in a cellular context and were used to test a Mn-complex which was shown to efficiently alter the flow of O(2)(-), ONOO(-) and H(2)O(2).Entities:
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Year: 2012 PMID： 22407398 DOI： 10.1039/c2dt12479c
Source DB: PubMed Journal: Dalton Trans ISSN： 1477-9226 Impact factor: 4.390