| Literature DB >> 22407236 |
Christian Schäfer1, Michel Miesch, Laurence Miesch.
Abstract
Intramolecular reductive coupling of cycloalkanones tethered to alkynoates in the presence of (η(2)-propene)titanium was successfully performed to provide hydroxy-esters in a diastereoselective manner. Subsequent lactonization afforded angularly fused unsaturated tricyclic lactones which represent relevant substructures of numerous bioactive compounds. This journal is © The Royal Society of Chemistry 2012Entities:
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Year: 2012 PMID： 22407236 DOI： 10.1039/c2ob07049a
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876