Literature DB >> 22405099

Bone healing after tooth extraction with or without an intervention: a systematic review of randomized controlled trials.

Kushel R Morjaria1, Ron Wilson, Richard M Palmer.   

Abstract

OBJECTIVES: To assess whether the use of a graft and/or membrane post-tooth extraction improves healing of the site dimensionally, radiographically, and/or histologically.
MATERIALS AND METHODS: MEDLINE and EMBASE and the Cochrane Central register of controlled trials (CENTRAL) were searched up until August 2011. Randomized controlled trials that included and compared healing post-tooth extraction between a control (no intervention) and a graft and/or membrane (test) were selected.
RESULTS: Titles and abstracts of 2,861 papers were screened. A total of 42 papers were selected for full text reading. Nine papers met the eligibility criteria and were selected for further analysis. Because of the varying graft materials used and the different methods of investigation, as well as the variation in follow-up times, a meta-analysis was not possible. The present review found that clinically, there was a range in loss of width in the control sites of 2.46 mm (SD 0.4 mm) to 4.56 mm (SD 0.33 mm) compared to 1.14 mm (SD 0.87 mm) to 2.5 mm (SD 1.2 mm) in the test sites. The range in loss of height in control sites was 0.9 mm (SD 1.6 mm) to 3.6 mm (SD 1.5 mm) compared to a gain of 1.3 mm (SD 2 mm) to a loss of 0.62 mm (SD 0.51 mm) in test sites. Radiographically a range of change in bone height of between 0.51 mm (No SD) to 1.17 mm (SD 1.23 mm) was noted in control sites compared to a change of between 0.02 mm (SD 1.2 mm) and 1 mm (SD 1.4 mm) in test sites.
CONCLUSION: There is limited data regarding the effectiveness of alveolar ridge preservation therapies when compared to the control. Overall the socket intervention therapies did reduce alveolar ridge dimensional changes post-extraction, but were unable to prevent resorption. Histology did demonstrate a large proportion of residual graft material that may account for some of the difference in alveolar ridge dimensions at follow up.
© 2012 Wiley Periodicals, Inc.

Keywords:  augmentation; bone loss; extraction socket; ridge preservation; systematic review

Mesh:

Year:  2012        PMID: 22405099     DOI: 10.1111/j.1708-8208.2012.00450.x

Source DB:  PubMed          Journal:  Clin Implant Dent Relat Res        ISSN: 1523-0899            Impact factor:   3.932


  33 in total

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2.  Immediate effects of tooth extraction on ridge integrity and dimensions.

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Review 4.  Effect of alveolar ridge preservation after tooth extraction: a systematic review and meta-analysis.

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7.  Influence of platelet-rich fibrin on wound healing and bone regeneration after tooth extraction: A clinical and radiographic study.

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10.  Tomographic evaluation of the effect of simvastatin topical use on alveolar bone microarchitecture, pain and swelling after mandibular third molar extraction: a randomized controlled trial.

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