Literature DB >> 22404524

Copper-catalyzed alkylation of benzoxazoles with secondary alkyl halides.

Peng Ren1, Isuf Salihu, Rosario Scopelliti, Xile Hu.   

Abstract

Copper-catalyzed direct alkylation of benzoxazoles using nonactivated secondary alkyl halides has been developed. The best catalyst is a new copper(I) complex (1), and the reactions are promoted by bis[2-(N,N-dimethylamino)ethyl] ether.

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Year:  2012        PMID： 22404524     DOI： 10.1021/ol300348w

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Scope and limitations of auxiliary-assisted, palladium-catalyzed arylation and alkylation of sp2 and sp3 C-H bonds.

Authors:  Enrico T Nadres; Gerson Ivan Franco Santos; Dmitry Shabashov; Olafs Daugulis
Journal:  J Org Chem       Date:  2013-09-19       Impact factor: 4.354

2.  Facile continuous process for gas phase halogen exchange over supported alkyl phosphonium salts.

Authors:  Priti Sharma; Yoel Sasson
Journal:  RSC Adv       Date:  2018-01-12       Impact factor: 3.361

3.  Copper-catalyzed direct alkylation of heteroarenes.

Authors:  Cédric Theunissen; Jianjun Wang; Gwilherm Evano
Journal:  Chem Sci       Date:  2017-03-20       Impact factor: 9.825
  3 in total

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