Literature DB >> 22404052

Unusual insertion and deletion at codon 67 and 69 of HIV type 1 subtype C reverse transcriptase among first-line highly active antiretroviral treatment-failing South Indian patients: association with other resistance mutations.

Shanmugam Saravanan1, Vidya Madhavan, Rami Kantor, Sathasivam Sivamalar, Selvamurthi Gomathi, Sunil S Solomon, Nagalingeswaran Kumarasamy, Davey M Smith, Robert T Schooley, Suniti Solomon, Pachamuthu Balakrishnan.   

Abstract

We report a high frequency of drug resistance mutations among patients with unusual insertions or deletions at the β(3)-β(4) hairpin-loop-coding region of HIV-1 subtype C reverse transcriptase, during failure of first-line antiretroviral therapy containing only reverse transcriptase inhibitors in Chennai, India.

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Year:  2012        PMID： 22404052      PMCID： PMC3505055          DOI： 10.1089/AID.2011.0331

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  14 in total

Review 1.  The causes and consequences of HIV evolution.

Authors:  Andrew Rambaut; David Posada; Keith A Crandall; Edward C Holmes
Journal:  Nat Rev Genet       Date:  2004-01       Impact factor: 53.242

2.  Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations.

Authors:  Jérôme Deval; Kirsten L White; Michael D Miller; Neil T Parkin; Jérôme Courcambeck; Philippe Halfon; Boulbaba Selmi; Joëlle Boretto; Bruno Canard
Journal:  J Biol Chem       Date:  2003-10-09       Impact factor: 5.157

Review 3.  Insertions and deletions in HIV-1 reverse transcriptase: consequences for drug resistance and viral fitness.

Authors:  Luis Menéndez-Arias; Tania Matamoros; Clara E Cases-González
Journal:  Curr Pharm Des       Date:  2006       Impact factor: 3.116

4.  Evolution of a novel 5-amino-acid insertion in the beta3-beta4 loop of HIV-1 reverse transcriptase.

Authors:  Marleen C D G Huigen; Loek de Graaf; Dirk Eggink; Rob Schuurman; Viktor Müller; Anna Stamp; David K Stammers; Charles A B Boucher; Monique Nijhuis
Journal:  Virology       Date:  2007-04-23       Impact factor: 3.616

Review 5.  Update of the drug resistance mutations in HIV-1: December 2010.

Authors:  Victoria A Johnson; Françoise Brun-Vézinet; Bonaventura Clotet; Huldrych F Günthard; Daniel R Kuritzkes; Deenan Pillay; Jonathan M Schapiro; Douglas D Richman
Journal:  Top HIV Med       Date:  2010-12

6.  Variants other than aspartic acid at codon 69 of the human immunodeficiency virus type 1 reverse transcriptase gene affect susceptibility to nuleoside analogs.

Authors:  M A Winters; T C Merigan
Journal:  Antimicrob Agents Chemother       Date:  2001-08       Impact factor: 5.191

7.  Relative replication fitness of a high-level 3'-azido-3'-deoxythymidine-resistant variant of human immunodeficiency virus type 1 possessing an amino acid deletion at codon 67 and a novel substitution (Thr-->Gly) at codon 69.

Authors:  T Imamichi; S C Berg; H Imamichi; J C Lopez; J A Metcalf; J Falloon; H C Lane
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

8.  Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids.

Authors:  S G Sarafianos; K Das; A D Clark; J Ding; P L Boyer; S H Hughes; E Arnold
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-31       Impact factor: 11.205

9.  Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.

Authors:  Lisa Ross; Neil Parkin; Colombe Chappey; Robin Fisher; Marty St Clair; Michael Bates; Margaret Tisdale; Ernest Randall Lanier
Journal:  AIDS       Date:  2004-08-20       Impact factor: 4.177

10.  Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel.

Authors:  Martin S Hirsch; Huldrych F Günthard; Jonathan M Schapiro; Françoise Brun-Vézinet; Bonaventura Clotet; Scott M Hammer; Victoria A Johnson; Daniel R Kuritzkes; John W Mellors; Deenan Pillay; Patrick G Yeni; Donna M Jacobsen; Douglas D Richman
Journal:  Clin Infect Dis       Date:  2008-07-15       Impact factor: 9.079
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  2 in total

1.  A Combination of Amino Acid Mutations Leads to Resistance to Multiple Nucleoside Analogs in Reverse Transcriptases from HIV-1 Subtypes B and C.

Authors:  Paul L Boyer; Catherine A Rehm; Michael C Sneller; JoAnn Mican; Margaret R Caplan; Robin Dewar; Andrea L Ferris; Patrick Clark; Adam Johnson; Frank Maldarelli; Stephen H Hughes
Journal:  Antimicrob Agents Chemother       Date:  2021-11-01       Impact factor: 5.938

2.  Capacity building and predictors of success for HIV-1 drug resistance testing in the Asia-Pacific region and Africa.

Authors:  Sally Land; Julian Zhou; Philip Cunningham; Annette H Sohn; Thida Singtoroj; David Katzenstein; Marita Mann; David Sayer; Rami Kantor
Journal:  J Int AIDS Soc       Date:  2013-07-10       Impact factor: 5.396
  2 in total

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